DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18754 and Klk8

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001100979.1	Gene:	Klk8 / 308565	RGDID:	1305998	Length:	260	Species:	Rattus norvegicus

Alignment Length:	252	Identity:	83/252 - (32%)
Similarity:	112/252 - (44%)	Gaps:	39/252 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 RDRGAENAELNE-----YPWMVLLLYENRL----SLI--RYVLTAAHCVIGGYLTQNDLVLKSVR 158
            |.:|::..|..|     .||...|....||    .|:  |:|||||||....|         |||
  Rat    27 RAQGSKILEGQECKPHSQPWQTALFQGERLVCGGVLVGDRWVLTAAHCKKDKY---------SVR 82

  Fly   159 LGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSG-GTYRNDIALLRLQFPVRYTKKIQPICLLD 222
            ||:.:    ..:...|..:::|.::..|..|.||. ..:.:||.|:|||.......|::||.|.:
  Rat    83 LGDHS----LQKRDEPEQEIQVARSIQHPCFNSSNPEDHSHDIMLIRLQNSANLGDKVKPIELAN 143

  Fly   223 AEFPLQDLNLQISGWDPTKSSQ-----TLITSTVKERNPADCLNRYPSFRSASQVCAGGQRKGDT 282
            . .|.......||||....|.|     ||..:.||..:...|...||...:...||||.....||
  Rat   144 L-CPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGSSNGADT 207

  Fly   283 CAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANL 339
            |.|.||.|   ::.:||     |.||.|:|...|.....|||||||..::.|||..:
  Rat   208 CQGDSGGP---LVCNGV-----LQGITSWGSDPCGKPEKPGVYTKICRYTNWIKKTM 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	82/246 (33%)
		Tryp_SPc	108..335	CDD:214473	79/243 (33%)
Klk8	NP_001100979.1	Tryp_SPc	32..252	CDD:214473	78/241 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910