DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and Prss42

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001100333.2	Gene:	Prss42 / 301027	RGDID:	1562548	Length:	340	Species:	Rattus norvegicus

Alignment Length:	259	Identity:	73/259 - (28%)
Similarity:	117/259 - (45%)	Gaps:	40/259 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 CGQTTPVFRDRGAENAELNEYPWMVLLLYENRL----SLI--RYVLTAAHCVIGGYLTQNDLVLK 155
            |||  |:.:..|..:||..::||.|.|...:..    ||:  ::|||||||:       :..|..
  Rat    77 CGQ--PLMKIMGGVDAEEGKWPWQVSLRVRHMHVCGGSLLNSQWVLTAAHCI-------HSRVQY 132

  Fly   156 SVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICL 220
            :|::|:.:.     ..:...|.:.:....||..| |:....:||||||:||.||.:|..|.|||:
  Rat   133 NVKMGDRSV-----YRQNTSLVIPIQNIFVHPKF-STTTVVQNDIALLKLQQPVNFTSSIHPICV 191

  Fly   221 LDAEFPLQ-DLNLQISGW-DPTKSSQTLITSTVKERNPA-----DCLNRYPSFRSAS-------Q 271
            ....|.:: .....::|| .|...:..:.|..::|.:.:     :|........|.|       .
  Rat   192 PTGTFHVKAGTKCWVTGWGKPDPGAPQIPTEILQEVDQSIILYEECNEMLKKMASTSVDLVKRGM 256

  Fly   272 VCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWI 335
            |||..:...|.|.|.||.|    :....|......|:.|:|.. |...|.|||||.:..:::|:
  Rat   257 VCAYKEGGKDACQGDSGGP----LSCEFDNRWVQIGVVSWGIG-CGRKGHPGVYTDVAFYNKWL 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	69/248 (28%)
		Tryp_SPc	108..335	CDD:214473	68/246 (28%)
Prss42	NP_001100333.2	Tryp_SPc	83..314	CDD:214473	68/248 (27%)
Prss42	NP_001100333.2	Tryp_SPc	84..315	CDD:238113	68/248 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910