DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and Tpsb2

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_062053.2	Gene:	Tpsb2 / 29268	RGDID:	3065	Length:	274	Species:	Rattus norvegicus

Alignment Length:	277	Identity:	78/277 - (28%)
Similarity:	118/277 - (42%)	Gaps:	66/277 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 PNKQTCGQTTPVFRDRGAENAELNEYPWMVLLLYENRL-------SLI--RYVLTAAHCVIGGYL 147
            |.||..|..       |...|..:::||.|.|.::...       |||  ::|||||||| |.::
  Rat    23 PVKQRVGIV-------GGREASESKWPWQVSLRFKFSFWMHFCGGSLIHPQWVLTAAHCV-GLHI 79

  Fly   148 TQNDLVLKSVRLGESTTDCITSESRCPHLD--VEVGQTTVH-QGFTSSGGTYRNDIALLRLQFPV 209
            ...:|....:|           |....:.|  :.|.:|.|| ..:|...|.   |||||.|:.||
  Rat    80 KSPELFRVQLR-----------EQYLYYADQLLTVNRTVVHPHYYTVEDGA---DIALLELENPV 130

  Fly   210 RYTKKIQPICLLDAE--FPLQDLNLQISGWDPTKSSQTL--------ITSTVKERNPADCLNRY- 263
            ..:..|.|..|..|.  || ...:..::||....|.:.|        :...:.|.:..|  .:|
  Rat   131 NVSTHIHPTSLPPASETFP-SGTSCWVTGWGDIDSDEPLLPPYPLKQVKVPIVENSLCD--RKYH 192

  Fly   264 ---------PSFRSASQVCAGGQRKGDTCAGISGSP-VMGIMGSGVDEFVFLAGIASYGQQYCYS 318
                     |..:. ..:|||..| .|:|.|.||.| |..:.|:.:.     ||:.|:|:. |..
  Rat   193 TGLYTGDDVPIVQD-GMLCAGNTR-SDSCQGDSGGPLVCKVKGTWLQ-----AGVVSWGEG-CAE 249

  Fly   319 AGIPGVYTKIGHFSEWI 335
            |..||:||::.::.:||
  Rat   250 ANRPGIYTRVTYYLDWI 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	74/261 (28%)
		Tryp_SPc	108..335	CDD:214473	72/259 (28%)
Tpsb2	NP_062053.2	Tryp_SPc	30..268	CDD:238113	74/270 (27%)
Tpsb2	NP_062053.2	Tryp_SPc	30..266	CDD:214473	72/268 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910