DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and F10

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_058839.1	Gene:	F10 / 29243	RGDID:	61850	Length:	482	Species:	Rattus norvegicus

Alignment Length:	363	Identity:	92/363 - (25%)
Similarity:	144/363 - (39%)	Gaps:	92/363 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SCQK-------DEKCTRLVSCSPLMNILRPRGMTQAEKDVFAHRQCGLDPNGHELLHMVYVCCPE 86
            ||.|       .:.|   :|.:|.     |.|.|...:   |.|...|:.:..|         |:
  Rat   150 SCAKGYFLGNDGKSC---LSTAPF-----PCGKTNKGR---AKRSVALNTSNSE---------PD 194

  Fly    87 LGDVLPNKQ------------TCGQTTP------VFRDRGAENAELNEYPWMVLLLYENRL---- 129
            ..|::|:..            ...:|.|      |.|..|.:..:..|.||..||..:...
  Rat   195 PEDLMPDADILYPTESPSELLNLNKTEPEANSDDVIRIVGGQECKRGECPWQALLFSDEETDGFC 259

  Fly   130 --SLIR--YVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFT 190
              :::.  |:||||||:       :......||:|    |..|.:.....:..||.....|..|.
  Rat   260 GGTILNEFYILTAAHCL-------HQAKRFKVRVG----DLNTEQEDGGEMVHEVDMIIKHNKFQ 313

  Fly   191 SSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEFPLQDLNLQ----ISGWDPT--KSSQTLITS 249
            ..  ||..|||:|||:.|:.:.:.:.|.||...::....|..|    :||:..|  |..|:.:..
  Rat   314 RD--TYDFDIAMLRLKTPITFRENVAPACLPQKDWAEATLMTQKTGIVSGFGRTHEKGRQSKVLK 376

  Fly   250 TVK----ERNPADCLNRYPSFRSASQ--VCAG-GQRKGDTCAGISGSPVMGIMGSGVDEFVFLAG 307
            .::    :||..    |..:..|.:|  .||| ..::.|.|.|.||.|.:    :...:..|:.|
  Rat   377 MMEVPYVDRNTC----RLSTSFSITQNMFCAGYDAKQEDACQGDSGGPHV----TRFKDTYFVTG 433

  Fly   308 IASYGQQYCYSAGIPGVYTKIGHFSEWI----KANLAP 341
            |.|:|:. |...|..|:|||:..|.:||    ||.:.|
  Rat   434 IVSWGEG-CARKGKYGIYTKVTAFLKWIDRSMKARVGP 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	10/48 (21%)
		Tryp_SPc	108..338	CDD:238113	70/254 (28%)
		Tryp_SPc	108..335	CDD:214473	67/247 (27%)
F10	NP_058839.1	GLA	23..84	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:405372	3/13 (23%)
		Tryp_SPc	232..462	CDD:238113	69/251 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010