DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and Habp2

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001001505.2	Gene:	Habp2 / 292126	RGDID:	1302979	Length:	558	Species:	Rattus norvegicus

Alignment Length:	369	Identity:	105/369 - (28%)
Similarity:	151/369 - (40%)	Gaps:	83/369 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 KCTRLVSCSPLM----NILRPRG----MTQAEKDVFAHRQCGLDPNG-HELLHMVYV-------- 82
            |.:|.|:.:|.:    ::|....    |..||....|......:|:| |:....|.|
  Rat   203 KVSRTVNQNPCLYWNSHLLLQENYNMFMEDAETHGIADHNFCRNPDGDHKPWCFVKVNSEKVKWE 267

  Fly    83 -C----CPE------LGDV------LPNKQTCGQTT----PVFRDRGAENAELNEYPWMVLLLYE 126
             |    |||      ||.:      ||...:||:|.    .|.|..|...:...::||.|.|...
  Rat   268 YCNVEVCPESDAANPLGSLQEPVMELPGFDSCGKTEMTEHAVKRIYGGFKSTAGKHPWQVSLQTS 332

  Fly   127 NRL------------SLIR--YVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCITSESRCPHLD 177
            ..|            |||.  :|||||||        .|:..|.:::.....|...:||......
  Rat   333 LPLTTSMPQGHFCGGSLIHPCWVLTAAHC--------TDMSTKHLKVVLGDQDLKKTESHEQTFR 389

  Fly   178 VEVGQTTVHQGFTSSGGTYRNDIALLRLQFPV-----RYTKKIQPICLLDAEFPLQDLNLQISGW 237
            ||  :...:..:........||||||:|: ||     ..:|.::.:||....|| ......||||
  Rat   390 VE--KILKYSQYNERDEIPHNDIALLKLK-PVGGHCALESKYVKTVCLPSDPFP-SGTECHISGW 450

  Fly   238 DPTKS---SQTLITSTVKERNPADCLNR--YPSFRSASQVCAGGQRK--GDTCAGISGSPVMGIM 295
            ..|::   |:.|:.:.||....|.|.:|  |......|.:|||..:|  .|||.|.||.|    :
  Rat   451 GVTETGEGSRQLLDAKVKLIANALCNSRQLYDHTIDDSMICAGNLQKPGSDTCQGDSGGP----L 511

  Fly   296 GSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANL 339
            ....|...::.||.|:||: |...  |||||::..|..|||..:
  Rat   512 TCEKDGTYYVYGIVSWGQE-CGKK--PGVYTQVTKFLNWIKTTM 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	15/70 (21%)
		Tryp_SPc	108..338	CDD:238113	78/255 (31%)
		Tryp_SPc	108..335	CDD:214473	75/252 (30%)
Habp2	NP_001001505.2	EGF_CA	71..107	CDD:238011
		KR	191..275	CDD:238056	15/71 (21%)
		Tryp_SPc	312..551	CDD:238113	78/257 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910