DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and Tmprss15

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_038944148.1	Gene:	Tmprss15 / 288291	RGDID:	1311046	Length:	1028	Species:	Rattus norvegicus

Alignment Length:	313	Identity:	88/313 - (28%)
Similarity:	131/313 - (41%)	Gaps:	78/313 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 PNGHELLHMVYVCCPELGDVLP-NKQTCGQ---TTPVF-RDRGAENAELNEYPWMVLLLYENR-- 128
            |||..:|.....|..:...:|. |.::||:   |..|. :..|..:.:...:||:|.|.|.:|
  Rat   749 PNGSLILTPSLQCSQDSLILLQCNHKSCGEKMVTQKVGPKIVGGSDTQAGAWPWVVALYYRDRSG 813

  Fly   129 ------LSLIR--YVLTAAHC-------------VIGGYLTQNDLVLKSVRLGESTTDCITSESR 172
                  .||:.  ::::||||             |:|.::..|   |.|.::.....|.|...
  Rat   814 DRLLCGASLVSSDWLVSAAHCVYRRNLDPTRWTAVLGLHMQSN---LTSPQVVRRVVDRIVIN-- 873

  Fly   173 CPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEFPLQDLNL----- 232
             ||.|..               ...||||::.|:|.|.||..||||||     |.::...
  Rat   874 -PHYDKR---------------RKVNDIAMMHLEFKVNYTDYIQPICL-----PEENQTFTPGRM 917

  Fly   233 -QISGWDPTKSSQTLITSTVKERNPAD--------CLNRYPSFR-SASQVCAGGQRKG-DTCAGI 286
             .|:||...|.:.......:||   ||        |..:.|.:. :.|.:|||.:..| |:|.|.
  Rat   918 CSIAGWGYNKINAGSTVDVLKE---ADVPLVSNEKCQQQLPEYDITESMLCAGYEEGGTDSCQGD 979

  Fly   287 SGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANL 339
            ||.|:|    ...:...||.|:.|:|.| |.....||||.::..|.|||.:.|
  Rat   980 SGGPLM----CQENNRWFLVGVTSFGVQ-CALPNHPGVYARVSQFIEWIHSFL 1027

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	4/12 (33%)
		Tryp_SPc	108..338	CDD:238113	76/268 (28%)
		Tryp_SPc	108..335	CDD:214473	74/265 (28%)
Tmprss15	XP_038944148.1	SEA	54..155	CDD:214554
		LDLa	188..221	CDD:238060
		CUB	229..335	CDD:412131
		MAM	351..507	CDD:395504
		CUB	528..635	CDD:395345
		LDLa	647..681	CDD:238060
		Tryp_SPc	789..1025	CDD:238113	76/269 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910