Protein Alignment CG18754 and TMPRSS12

DIOPT Version :9

• Sequence 1: NP_652652.3
• Gene: CG18754 / 59145
• FlyBaseID: FBgn0042106
• Length: 341
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 86/296 - (29%)
• Similarity: 120/296 - (40%)
• Gaps: 64/296 - (21%)

  Fly    63 AHRQ-CGLDPNGHELLHMVYVCCPELGDVLPNKQTCGQTTPVFRDRGAENAELNEYPWMVLLLYE 126
            ||.: ||..|               |.|||...:..|.|          .|:...:||:|.|..:
Human    59 AHAEDCGTAP---------------LKDVLQGSRIIGGT----------EAQAGAWPWVVSLQIK 98

  Fly   127 NRLSLI----------RYVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCITSESRCPHL-DVEV 180
            ....|:          |:|||||||.    ...:|.::.:..:|.:..     ..|.||. .:::
Human    99 YGRVLVHVCGGTLVRERWVLTAAHCT----KDASDPLMWTAVIGTNNI-----HGRYPHTKKIKI 154

  Fly   181 GQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEFPLQDLNLQ--ISGWDPTK-- 241
            ....:|..|...  :|.|||||..|:..|||...||||||....|.:.|.|.:  ||||..||
Human   155 KAIIIHPNFILE--SYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEE 217

  Fly   242 SSQTLITSTVK----ERNPADCLNRYPSFRSASQVCAGGQRKG-DTCAGISGSPVMGIMGSGVDE 301
            .:.|.|....:    .|...:....|......:..|||.:... |||.|.||.|:|..:    .|
Human   218 GNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYL----PE 278

  Fly   302 F--VFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWI 335
            :  .|:.||.|||.. |...|.||||.....:.:|:
Human   279 YKRFFVMGITSYGHG-CGRRGFPGVYIGPSFYQKWL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	5/21 (24%)
		Tryp_SPc	108..338	CDD:238113	75/250 (30%)
		Tryp_SPc	108..335	CDD:214473	74/248 (30%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..63		2/3 (67%)
		Tryp_SPc	78..316	CDD:238113	77/262 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910