DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and Proc

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_008770240.3	Gene:	Proc / 25268	RGDID:	3411	Length:	500	Species:	Rattus norvegicus

Alignment Length:	318	Identity:	98/318 - (30%)
Similarity:	135/318 - (42%)	Gaps:	76/318 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 RQCGLDPNGHELL--HM-----VYVCCPELGDVLPNKQTCGQTTPVFRDRGAENAEL-------- 114
            |:|...| |:||.  ||     |...|.:|.     |:|..:.....||...|:.||
  Rat   196 RRCACAP-GYELADDHMHCRPTVNFPCGKLW-----KRTDKKRKNFKRDIDPEDEELELGPRIVN 254

  Fly   115 ------NEYPWMVLLLYENR-------LSLIRYVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDC 166
                  .:.||..:||...:       |....:|||||||:      ::...| :|||||
  Rat   255 GTLTKQGDSPWQAILLDSKKKLACGGVLIHTSWVLTAAHCL------ESSKKL-TVRLGE----- 307

  Fly   167 ITSESRCP-HLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICL----LDAEFP 226
            .....|.| .||:::.:..||..:|.|...  ||||||||..|...:|.|.||||    |..|..
  Rat   308 YDLRRRDPWELDLDIKEVLVHPNYTRSNSD--NDIALLRLSQPATLSKTIVPICLPNSGLAQELS 370

  Fly   227 LQDLNLQISGW----DPTKSSQ-------TLITSTVKERNPADCLNRYPSFRSASQVCAG--GQR 278
            .......::||    |..|..:       |.|...:..||  ||:....:..|.:.:|||  |..
  Rat   371 QAGQETVVTGWGYQSDKVKDGRRNRTFILTFIRIPLAARN--DCMQVMNNVVSENMLCAGIIGDT 433

  Fly   279 KGDTCAGISGSP-VMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWI 335
            : |.|.|.||.| |:...|:.     ||.|:.|:|:. |......|||||:|.:.:||
  Rat   434 R-DACDGDSGGPMVVFFRGTW-----FLVGLVSWGEG-CGHLNNYGVYTKVGSYLKWI 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	9/25 (36%)
		Tryp_SPc	108..338	CDD:238113	83/268 (31%)
		Tryp_SPc	108..335	CDD:214473	81/266 (30%)
Proc	XP_008770240.3	GLA	65..125	CDD:214503
		EGF_CA	126..170	CDD:238011
		FXa_inhibition	178..213	CDD:405372	8/17 (47%)
		Tryp_SPc	252..486	CDD:238113	80/256 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910