DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CG30098

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_725573.2	Gene:	CG30098 / 246456	FlyBaseID:	FBgn0050098	Length:	264	Species:	Drosophila melanogaster

Alignment Length:	257	Identity:	78/257 - (30%)
Similarity:	107/257 - (41%)	Gaps:	49/257 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 VFRDR--GAENAELNEYPWMVLLLYENRL----SLI--RYVLTAAHCVIGGYLTQNDLVLKSVRL 159
            :||.|  |.:||  ...|||..|:.:||.    |||  |:|||||||.     ..||.:.  |||
  Fly    32 LFRIRVIGGQNA--RRTPWMAYLIRDNRFACGGSLIAYRFVLTAAHCT-----KINDNLF--VRL 87

  Fly   160 GE----STTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRN-DIALLRLQFPVRYTKKIQPIC 219
            ||    .|||..|...|       |.....|:.:..    :|| |||:|:|...|.|...|:|||
  Fly    88 GEYDSSRTTDGQTRSYR-------VVSIYRHKNYID----FRNHDIAVLKLDRQVVYDAYIRPIC 141

  Fly   220 LLDAEFPLQDL-----NLQISGWDPTKSSQTLITSTVKERNPADCLNRYPSFRSASQVCAGGQRK 279
            :| ....||.|     |..::||........:.| |::|.:.....|.|....|.|..|....:.
  Fly   142 IL-LNSGLQSLANSIQNFTLTGWGQMAHYYKMPT-TLQEMSLRRVRNEYCGVPSLSICCWNPVQY 204

  Fly   280 GDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYC--YSAGIPGVYTKIGHFSEWIKANL 339
              .|.|.||.|:..::..|........|:.:.....|  ||:     |..:..:..|:...|
  Fly   205 --ACFGDSGGPLGSLVKYGHKTIYVQFGVTNSVTGNCDGYSS-----YLDLMSYMPWLYQTL 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	74/247 (30%)
		Tryp_SPc	108..335	CDD:214473	73/244 (30%)
CG30098	NP_725573.2	Tryp_SPc	36..254	CDD:214473	74/246 (30%)
CG30098	NP_725573.2	Tryp_SPc	37..258	CDD:238113	74/249 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463654
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940