DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CG30091

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	248	Identity:	79/248 - (31%)
Similarity:	109/248 - (43%)	Gaps:	43/248 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 GAENAELNEYPWMVLLLYENRL----SLI--RYVLTAAHCVIGGYLTQNDLVLK----SVRLGES 162
            |.:..||.. |||.|:...:..    |:|  ::|||||||:    .|..:.::|    :|.||..
  Fly    40 GVDAGELKN-PWMALIKTNDEFICGGSVITNKFVLTAAHCM----CTDEECIVKYTQLTVTLGVY 99

  Fly   163 TTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLL--DAEF 225
            .. ..|.|...||....|.:..:|..|...  .|||||||||||..:.|..:|:|:|:|  |...
  Fly   100 HL-LATGEHNHPHEIYNVERVYIHDSFAIQ--NYRNDIALLRLQKSIVYKPQIKPLCILLNDQLK 161

  Fly   226 PLQDLNLQIS--GWDPT---KSSQTLITSTVKERNPADC------LNRYPSFRSASQVCAGGQRK 279
            |..||..:.:  ||..|   |.|..|....:...:...|      ...||.|      |||....
  Fly   162 PQTDLIQEFTAIGWGVTGNGKMSNNLQMVKIYRIDRKMCEAAFWYTFDYPMF------CAGTAVG 220

  Fly   280 GDTCAGISGSPV-MGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKI-GH 330
            .|||...||.|: :.::..|:.....| ||.|.|.:.|...   |:||.: ||
  Fly   221 RDTCKRDSGGPLYIHMLFDGIKRATQL-GIVSTGTEDCRGF---GMYTDVMGH 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	79/248 (32%)
		Tryp_SPc	108..335	CDD:214473	79/248 (32%)
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	79/248 (32%)
		Tryp_SPc	37..276	CDD:238113	79/248 (32%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463566
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940