DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CG30087

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_725489.2	Gene:	CG30087 / 246446	FlyBaseID:	FBgn0050087	Length:	277	Species:	Drosophila melanogaster

Alignment Length:	262	Identity:	84/262 - (32%)
Similarity:	121/262 - (46%)	Gaps:	42/262 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 CG---QTTPVFRDRGAENAELNEYPWMVLLLYENRLSLI---------RYVLTAAHCVIGGYLTQ 149
            ||   ::....|....:.|.:...|:||   |....||.         ||:|||||||....
  Fly    30 CGVTYESQTAMRVVNGKEAVIRSAPFMV---YVTNNSLTHCGGSILNSRYILTAAHCVFPNL--- 88

  Fly   150 NDLVLKSVRLGEST--TDCITSESRCPHLDVEVG--QTTVHQGFTSSGGTYRNDIALLRLQFPVR 210
                  .:||||..  ||.....|.|.....|.|  :...|:.:.::  .:.||||||:|...:.
  Fly    89 ------RLRLGEHNIRTDPDCQGSNCSPRSEEYGIMKAITHRFYNAA--NHVNDIALLKLNRSIN 145

  Fly   211 YTKKIQPICLL--DAEFPLQDLNLQISGWDPTKSS---QTLITSTVKERNPADCLNRYPSFRSAS 270
            :...|||||:|  .|..| .....|..||..||.:   ..|.|:.::..:.|.|...:.::.:.:
  Fly   146 FNVHIQPICILLNPASAP-SVATYQTFGWGETKKNGFPHLLQTAELRAYDAAYCSRSFHAYMNGN 209

  Fly   271 QVCAGGQRKGDTCAGISGSP-VMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEW 334
            |:|||.:.: |||||.||.| |..:...||..::.| ||.|||...|.|   |||||.:.::..|
  Fly   210 QICAGHEER-DTCAGDSGGPLVTRVDFDGVKRYLQL-GIVSYGPTDCQS---PGVYTYVPNYINW 269

  Fly   335 IK 336
            |:
  Fly   270 IR 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	81/248 (33%)
		Tryp_SPc	108..335	CDD:214473	79/245 (32%)
CG30087	NP_725489.2	Tryp_SPc	41..270	CDD:214473	80/248 (32%)
CG30087	NP_725489.2	Tryp_SPc	42..272	CDD:238113	81/250 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463599
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940