DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and try-4

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_508030.4	Gene:	try-4 / 185148	WormBaseID:	WBGene00006622	Length:	324	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	62/264 - (23%)
Similarity:	106/264 - (40%)	Gaps:	69/264 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 ENAELNEYPWMVLLLYE--NRL--SLIR--YVLTAAHCVIGGYLT----------------QNDL 152
            :.:::..:||.|....:  |||  |:|.  :::||||    |::|                .|..
Worm    51 QESKIKNFPWAVSFTVDGVNRLGGSIISPYHIITAAH----GFITTIGSRGNLCENKNWKKPNSS 111

  Fly   153 VLKSVRLGEST-------------TDCITSESRCPHLDV---EVGQTTVHQGFTSSGGTYRNDIA 201
            :.:|::....|             ||...::.||...||   :|....|...|.||.....:|.|
Worm   112 IYRSIKFLRDTRKVAYGGTCIRGHTDKYPNDPRCKKSDVIHNKVRAVLVDGEFASSNCLKGHDWA 176

  Fly   202 LLRLQFPVRYTKKIQPICLLDAEFPLQDL----NLQISGWDPT---KSSQTLITSTVKERNPADC 259
            ::.::..:.:::.::||||     |..::    :|.:.||..:   ..|..|| ..:..|...||
Worm   177 IVEVEKRIHFSENVRPICL-----PRPNMYYTKSLAVPGWGRSYIFNESGPLI-HEIPMRIDRDC 235

  Fly   260 ----LNRYPS----FRSASQVCAGGQRKGDTCAGISGSPVMGIMGSGVDEF--VFLAGIASYGQQ 314
                .:|.|:    |..|:.:.........||.|.||    |.:....|.:  .||..|.|:|.:
Worm   236 KRPWSDRLPADADDFICATSMNVSNYSAPRTCHGDSG----GGLEYRDDNYGRAFLIAITSFGTR 296

  Fly   315 YCYS 318
            .|.|
Worm   297 GCPS 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	62/264 (23%)
		Tryp_SPc	108..335	CDD:214473	62/264 (23%)
try-4	NP_508030.4	Tryp_SPc	51..318	CDD:238113	62/264 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010