DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and Tpsb2

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_034911.3	Gene:	Tpsb2 / 17229	MGIID:	96942	Length:	276	Species:	Mus musculus

Alignment Length:	264	Identity:	73/264 - (27%)
Similarity:	115/264 - (43%)	Gaps:	65/264 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 GAENAELNEYPWMVLLLYENRL-------SLI--RYVLTAAHCVIGGYLTQNDLVLKSVRLGEST 163
            |...|..:::||.|.|.::...       |||  ::|||||||| |.::....|.  .|:|.|..
Mouse    34 GGHEASESKWPWQVSLRFKLNYWIHFCGGSLIHPQWVLTAAHCV-GPHIKSPQLF--RVQLREQY 95

  Fly   164 T---DCITSESRC---PHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLD 222
            .   |.:.|.:|.   ||.            :|:.||.   |:|||.|:.||..:..:.||.|..
Mouse    96 LYYGDQLLSLNRIVVHPHY------------YTAEGGA---DVALLELEVPVNVSTHLHPISLPP 145

  Fly   223 AE--FPLQDLNLQISGWDPTKSSQTL--------ITSTVKERNPADCLNRY----------PSFR 267
            |.  || ...:..::||....:.:.|        :...:.|.:..|  .:|          |...
Mouse   146 ASETFP-PGTSCWVTGWGDIDNDEPLPPPYPLKQVKVPIVENSLCD--RKYHTGLYTGDDFPIVH 207

  Fly   268 SASQVCAGGQRKGDTCAGISGSP-VMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHF 331
            . ..:|||..|: |:|.|.||.| |..:.|:.:.     ||:.|:|:. |.....||:||::.::
Mouse   208 D-GMLCAGNTRR-DSCQGDSGGPLVCKVKGTWLQ-----AGVVSWGEG-CAQPNKPGIYTRVTYY 264

  Fly   332 SEWI 335
            .:||
Mouse   265 LDWI 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	73/264 (28%)
		Tryp_SPc	108..335	CDD:214473	71/262 (27%)
Tpsb2	NP_034911.3	Tryp_SPc	32..270	CDD:238113	73/264 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910