DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP001199

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_321960.2	Gene:	AgaP_AGAP001199 / 1281970	VectorBaseID:	AGAP001199	Length:	268	Species:	Anopheles gambiae

Alignment Length:	255	Identity:	68/255 - (26%)
Similarity:	105/255 - (41%)	Gaps:	48/255 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 GAENAELNEYPWMVLLL--YENRL---------SLI--RYVLTAAHCVIGGYLTQNDLVLKSVRL 159
            |.|.|..:|:|:.:.|.  |.|..         |||  ::||||.|||            .|...
Mosquito    29 GGEEAIAHEFPYQISLQWNYNNDEQDPFHFCGGSLIAEKFVLTAGHCV------------PSAIS 81

  Fly   160 GESTTDCITSESRCPHLDV-----EVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPIC 219
            .:...:.:..|......|.     .:.:..||:.:..|.|.  ||||:.|:..|....:.||.:.
Mosquito    82 PDGFPEAVAGEHDFSQYDAGVQRRRIAEMYVHEDYEGSVGP--NDIAIFRVDKPFHLNRNIQLVT 144

  Fly   220 LLDAE-FPLQDLNLQISGWDPTKSS------QTLITSTVKERNPADCLNRYPSFRSA-SQVCAGG 276
            |.:.. .|..:..  ||||..|..|      ..|:.:|:...:...|...|.:...| |.:|||.
Mosquito   145 LPEPNAIPTGETT--ISGWGSTSFSFEPSYPNILMKTTLPIMDLEVCRKIYFTETVADSNICAGT 207

  Fly   277 -QRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWI 335
             :.....|:|.||.|::.|     |:.:...||.|:|...|.....|||:.::.:|.:||
Mosquito   208 MEGTSSVCSGDSGGPLVQI-----DDEIVQVGIVSWGGIPCGGYKNPGVFVRVSYFIDWI 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	68/255 (27%)
		Tryp_SPc	108..335	CDD:214473	66/253 (26%)
AgaP_AGAP001199	XP_321960.2	Tryp_SPc	26..262	CDD:214473	66/253 (26%)
AgaP_AGAP001199	XP_321960.2	Tryp_SPc	27..265	CDD:238113	68/255 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910