DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP001395

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_321740.5	Gene:	AgaP_AGAP001395 / 1281782	VectorBaseID:	AGAP001395	Length:	268	Species:	Anopheles gambiae

Alignment Length:	242	Identity:	66/242 - (27%)
Similarity:	101/242 - (41%)	Gaps:	66/242 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 RYVLTAAHCVIGG---YLTQNDL--VLKSVRLGESTTDCITSESRCPHLD--VEVGQTTV--HQG 188
            |::|||.|||..|   .|..|.:  ||...|..|...:.|.|:   |..|  .|||..|:  |.|
Mosquito    45 RWLLTAGHCVCSGVNKILRANQIQAVLGLYRRSEFGGNQIDSD---PFSDRAYEVGIRTIVPHPG 106

  Fly   189 FTSSGGTYRNDIALLRLQFPVRYTKKIQPICL---LDAEFPLQDLNLQISGWDPTKSSQTLITST 250
            :..:..:  ||||||.|...:.::..::||||   .|....::.....::||...:.::.|
Mosquito   107 YVCNKPS--NDIALLELARRIDFSASVRPICLSSGADGSARVEGQTAVVAGWGWQQENRNL---- 165

  Fly   251 VKERNPADCLNR--YPSFR-----------------SASQVCAGGQRKG-DTCAGISGSP----- 290
               .:.||.|.|  ...||                 :.:|:|||....| |.|...||.|
Mosquito   166 ---GDKADTLQRAVVDVFRNEECESMYRRGNRSRTIARTQLCAGKGTGGVDACWADSGGPLVTSD 227

  Fly   291 --VMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWI 335
              ::||:.:|:.               |...|.||:||::..::.||
Mosquito   228 NVLIGIVSTGIG---------------CARPGFPGIYTRVSEYASWI 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	66/242 (27%)
		Tryp_SPc	108..335	CDD:214473	64/240 (27%)
AgaP_AGAP001395	XP_321740.5	Tryp_SPc	11..259	CDD:214473	64/240 (27%)
AgaP_AGAP001395	XP_321740.5	Tryp_SPc	12..259	CDD:238113	64/240 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910