DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP011669

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_320844.4	Gene:	AgaP_AGAP011669 / 1280970	VectorBaseID:	AGAP011669	Length:	576	Species:	Anopheles gambiae

Alignment Length:	288	Identity:	75/288 - (26%)
Similarity:	119/288 - (41%)	Gaps:	75/288 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 NKQTCGQTTPV--FRDRGAENAELNEYPWMVLLLY----------------ENRLSLIRYVLTAA 139
            |..|||:...|  :......:|:...:||.|.|.:                ||.      :|||:
Mosquito    26 NHLTCGKRKVVSQYLIHNGIDAKAGHWPWHVALFHRKDAQYEYACGGSILDENT------ILTAS 84

  Fly   140 HCVIGGYLTQNDLVLKS--------VRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTY 196
            |||    .||:.::..|        :.|.||      ||....||   |.:..||.||  |..:.
Mosquito    85 HCV----YTQSGVISISRVSVDVGRIHLNES------SEYTQTHL---VREIIVHPGF--SKNSI 134

  Fly   197 RNDIALLRLQFPVRYTKKIQPICL--LDAEFPLQDL----NLQISGWDPTKSSQTLITSTVKER- 254
            .|||||::|...:...|.:||:||  :|:.   |:|    |..|.|:.  .:.|.:::..:|:.
Mosquito   135 VNDIALIKLSSNITMNKYVQPVCLWTMDSN---QELIVGRNGTIVGFG--VNEQDVVSEQLKQAL 194

  Fly   255 ----NPADCL----NRYPSFRSASQVCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASY 311
                :|..|:    ..:.:..::...|..||:....|.|.||..:...:|..    .|:.|:.|:
Mosquito   195 IGVVDPLSCIADDRGVFGTHLTSDMFCGKGQKGVSACNGDSGGGMFFEIGGK----WFVRGLVSF 255

  Fly   312 ---GQQYCYSAGIPGVYTKIGHFSEWIK 336
               |.:.|.|.. ...||.:..:.||||
Mosquito   256 TPLGTEQCDSLK-NTAYTDVAKYLEWIK 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	70/271 (26%)
		Tryp_SPc	108..335	CDD:214473	67/268 (25%)
AgaP_AGAP011669	XP_320844.4	Tryp_SPc	41..282	CDD:238113	68/271 (25%)
		Tryp_SPc	43..281	CDD:214473	67/268 (25%)
		Tryp_SPc	330..568	CDD:214473
		Tryp_SPc	330..568	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910