DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP011719

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_320793.4	Gene:	AgaP_AGAP011719 / 1280920	VectorBaseID:	AGAP011719	Length:	762	Species:	Anopheles gambiae

Alignment Length:	234	Identity:	65/234 - (27%)
Similarity:	105/234 - (44%)	Gaps:	47/234 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 LLYENRLSLIRYVLTAAHCVIGGYLTQNDLVLKS--VRLG-----ESTTDCITSESRCPHLDVEV 180
            |::||      |:||||||     ....|.:|..  :|:|     ::..|....|.:.    |::
Mosquito    53 LIWEN------YILTAAHC-----YADPDTILSPDVIRIGDLNLFDADDDEFVQERKI----VQI 102

  Fly   181 GQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICL-LDAEFPLQDLNLQISGWDPT---- 240
            .:..:|     :..|...|:|||:|...|..::.:.|.|| ||...|..  .|:::||..|
Mosquito   103 IRHPLH-----NASTVYYDLALLKLDKKVIQSEGVIPTCLWLDDSIPFS--TLEVAGWGQTGFGK 160

  Fly   241 KSSQTLITSTVKERNPADCLNRYPSFRSA---------SQVCAGGQRKGDTCAGISGSPVMGIMG 296
            :.|..|:.:.:|.....:|. :|.:.|:.         .|:||..:.. |||.|.||.|:...:.
Mosquito   161 EKSNMLLKAELKLMTNTECA-KYNNKRTQRRLGNDLADHQLCAWDEVM-DTCPGDSGGPLHYNLY 223

  Fly   297 SGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWI 335
            ....:..||.|:.|:|:....|.  ||||.|:..|.:||
Mosquito   224 YKHTKIPFLVGVTSFGKACAVSQ--PGVYVKVAKFKQWI 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	65/234 (28%)
		Tryp_SPc	108..335	CDD:214473	63/232 (27%)
AgaP_AGAP011719	XP_320793.4	Tryp_SPc	19..263	CDD:238113	65/234 (28%)
		Tryp_SPc	19..260	CDD:214473	63/232 (27%)
		Tryp_SPc	318..537	CDD:304450
		Tryp_SPc	653..>762	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910