DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CLIPA6

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_320728.3	Gene:	CLIPA6 / 1280860	VectorBaseID:	AGAP011789	Length:	427	Species:	Anopheles gambiae

Alignment Length:	280	Identity:	87/280 - (31%)
Similarity:	117/280 - (41%)	Gaps:	69/280 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 FRDRGAEN--AELNEYPWMVLLLYENRL-------------SLI--RYVLTAAHCVIGGYLTQND 151
            ||..|::|  ||..|:||||.:|....:             |||  :.|||.||||.....:|
Mosquito   161 FRITGSKNSEAEYGEFPWMVAILKTEEVLGQLRENVYTCGGSLIHRQVVLTGAHCVQNKQPSQ-- 223

  Fly   152 LVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQ 216
              || ||:||..|.  |.....||.|..|.:..||..:...|  ..||:|||.|..||...:.||
Mosquito   224 --LK-VRVGEWDTQ--TKNEIYPHQDRSVVEIVVHPDYYKGG--LHNDVALLFLNAPVEPNESIQ 281

  Fly   217 PICLLDAEFPLQDLNLQ-----ISGWD----------------------PTKSSQTLITSTVKER 254
            .:||     |.||:...     .|||.                      |....||.:.:|  ..
Mosquito   282 TVCL-----PPQDMAFNHETCFASGWGKDVFGKAGTYQVILKKIDLPVVPNDQCQTALRTT--RL 339

  Fly   255 NPADCLNRYPSFRSASQVCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSA 319
            .|.  .|.:.||     :||||....|||.|..|||::..:.:....: :..|:.::|.. |...
Mosquito   340 GPK--FNLHKSF-----ICAGGVPGKDTCKGDGGSPLVCPIPNSPHHY-YQTGLVAWGIG-CGEN 395

  Fly   320 GIPGVYTKIGHFSEWIKANL 339
            ||||||..:..|..||..::
Mosquito   396 GIPGVYANVAKFRGWIDQHM 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	85/273 (31%)
		Tryp_SPc	108..335	CDD:214473	83/270 (31%)
CLIPA6	XP_320728.3	Tryp_SPc	162..411	CDD:214473	84/273 (31%)
CLIPA6	XP_320728.3	Tryp_SPc	169..414	CDD:238113	83/269 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910