DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CLIPA2

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_320727.4	Gene:	CLIPA2 / 1280859	VectorBaseID:	AGAP011790	Length:	503	Species:	Anopheles gambiae

Alignment Length:	295	Identity:	96/295 - (32%)
Similarity:	130/295 - (44%)	Gaps:	55/295 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 PELGDVLPNKQTCGQTTP---VFRDRGAEN--------------AELNEYPWMVLL--LYENRL- 129
            |...|..|......|.||   .::|.|..|              ||..|:||||.|  |.|.|.
Mosquito   200 PNAADPPPTPALTAQFTPESFSYQDCGQLNLNGVVQRTINEDFRAEYGEFPWMVALFQLPEQRYC 264

  Fly   130 ---SLI--RYVLTAAHCVIG-GYLTQNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQG 188
               :||  :.:||.||||.. |....|.:    ||.||..... |.|...|..|  :|..:|||.
Mosquito   265 CNGALIDPKAILTTAHCVTNCGGRAANIM----VRFGEWNMSS-THEMAIPRED--IGVKSVHQH 322

  Fly   189 FTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEFPLQDL-NLQISGW-----DPTKSSQTLI 247
            ...|.....|:||:|.|..||:|...|||:||..|..||:.: |:..:||     :....:|.|.
Mosquito   323 PRYSPSALLNNIAVLELAHPVQYQATIQPVCLPSANQPLRAMENMIATGWGRVMEENAPPTQILK 387

  Fly   248 TSTVKERNPADC---LNR----YPSFRSASQVCA----GGQRKGDTCAGISGSPVMGIMGSGVDE 301
            ...::...|:.|   |.|    ||....:|.||:    |.|.:  .|.|.:|:||: :...|...
Mosquito   388 RLDLQRMEPSICREALRRVRRPYPFILDSSFVCSTTNHGDQER--PCDGDAGAPVV-VELPGTTN 449

  Fly   302 FVFLAGIASYGQQYCYSAGIP-GVYTKIGHFSEWI 335
            ..:|.|:.|:|.. |:...|| .|.||:.||.|||
Mosquito   450 RYYLHGLVSWGYG-CHQKQIPYTVLTKVVHFREWI 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	89/269 (33%)
		Tryp_SPc	108..335	CDD:214473	87/267 (33%)
CLIPA2	XP_320727.4	Tryp_SPc	244..486	CDD:238113	87/251 (35%)
CLIPA2	XP_320727.4	Tryp_SPc	244..483	CDD:214473	85/249 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910