DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP011910

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_320619.4	Gene:	AgaP_AGAP011910 / 1280754	VectorBaseID:	AGAP011910	Length:	408	Species:	Anopheles gambiae

Alignment Length:	255	Identity:	73/255 - (28%)
Similarity:	110/255 - (43%)	Gaps:	49/255 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 GAENAELNEYPWMVLLLYENRLSLI--------RYVLTAAHCVIGGYLTQNDLVL----KSVRLG 160
            |.|.| :||:|.|..|:.....::|        .|.||||||::  ..|.||.||    .:::.|
Mosquito   169 GVETA-VNEFPMMAALIDVKTKTVICGATIVTNSYALTAAHCLL--QRTVNDTVLLVGDHNIKTG 230

  Fly   161 ESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEF 225
               ||  ||.|:.    ..|.|...|.|||..  ...|||||:|...|::|...:.|.||
Mosquito   231 ---TD--TSFSQV----YIVAQFMSHPGFTVR--PVANDIALVRTGRPIQYNPGVGPACL----- 279

  Fly   226 P-------LQDLNLQISGWDPTKSSQTLITSTVKER----NPADCLNRYPSFRSASQVCAGGQRK 279
            |       .:...::.:||..........|:..|.:    ...:|..|..:.....|:|.....:
Mosquito   280 PWSYTTQSFEGRTVEATGWGDLDFGGPRATALNKVQLAVIGNQECSQRLSASVPYQQLCTYTANR 344

  Fly   280 GDTCAGISGSPVMGI-MGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKAN 338
             |||.|.||.|:... :.:|:   ::..||.|:|.. |.:|. |.|.|::..:.:||..|
Mosquito   345 -DTCQGDSGGPLFFTNLANGL---LYDVGIVSFGIA-CATAN-PSVNTRVTEYLDWIMVN 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	72/253 (28%)
		Tryp_SPc	108..335	CDD:214473	70/250 (28%)
AgaP_AGAP011910	XP_320619.4	CUB	27..146	CDD:238001
		Tryp_SPc	165..395	CDD:214473	70/250 (28%)
		Tryp_SPc	166..396	CDD:238113	71/251 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910