DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP011912

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_320615.4	Gene:	AgaP_AGAP011912 / 1280750	VectorBaseID:	AGAP011912	Length:	408	Species:	Anopheles gambiae

Alignment Length:	244	Identity:	64/244 - (26%)
Similarity:	108/244 - (44%)	Gaps:	43/244 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 LNEYPWMVLLLYENRLSLI--------RYVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCITSE 170
            :||:|.|..|:..:..|:.        .:.:|||||:.|..|:.:.|::....|...|.   ||.
Mosquito   178 VNEFPMMAGLVDSSSRSVFCGATIISDYHSITAAHCMRGRSLSASGLLVGDHNLSVGTD---TSY 239

  Fly   171 SRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEFPLQDLN---- 231
            |    :.:.:...|.|..:..|..  ||||||:|....:.:...:.|.||   .|.....|
Mosquito   240 S----VLMRLASITNHPQYVVSPS--RNDIALVRTADRIAFNAAVGPACL---PFRYSTSNFAGS 295

  Fly   232 -LQISGWD------PTKSSQTLIT-STVKERNPADCLNRYPSFRSASQVCAGGQRKGDTCAGISG 288
             ::.:||.      ||.:....:: :.:.|::   |.:..|:. .||.:|.....| |||...||
Mosquito   296 IVEATGWGTMDFGAPTSNVLRKVSLNVISEQS---CQSSMPNI-LASHICTYTPGK-DTCQYDSG 355

  Fly   289 SPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKA 337
            .|::...|..    |:|.|:.:||.. |.|:. |.|.::|..:..||::
Mosquito   356 GPLLFTTGGR----VYLVGVVNYGVS-CASSK-PSVSSRITSYLSWIQS 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	64/244 (26%)
		Tryp_SPc	108..335	CDD:214473	62/240 (26%)
AgaP_AGAP011912	XP_320615.4	CUB	55..155	CDD:238001
		Tryp_SPc	169..396	CDD:214473	62/240 (26%)
		Tryp_SPc	170..399	CDD:238113	64/244 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910