DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18754 and AgaP_AGAP012270

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_320269.4	Gene:	AgaP_AGAP012270 / 1280418	VectorBaseID:	AGAP012270	Length:	862	Species:	Anopheles gambiae

Alignment Length:	306	Identity:	70/306 - (22%)
Similarity:	123/306 - (40%)	Gaps:	65/306 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 LLHMVYVCCPELGDVLPNKQTCG--QTTPVFRDRGAENAELNEYPWMVLLLYENRLSLIRYVLTA 138
            ||.:..|.|.....|..|:..||  :...|:......:|....:||.. ::|:.......|
Mosquito     8 LLLLSGVLCVWSQTVGVNRLVCGRRKVKSVYLIHNGIDAMPGHWPWHA-VIYQRANGAEEY---- 67

  Fly   139 AHCVIGGYLTQNDLVLKSVRLGESTTDCITSESRC---PHLDVEVGQTTVHQ--GFTSSGGT--- 195
             .|  ||.:...|.:|.|       ..|:|..||.   ..|.:|||:..:|:  .:|.:.|.
Mosquito    68 -KC--GGSIIDEDTILTS-------GHCVTVGSRAISPEQLSIEVGRIRLHERTEYTQTHGVRQV 122

  Fly   196 ----------YRNDIALLRLQFPVRYTKKIQPICL--LDAEFPLQDL----NLQISGWDPTKSSQ 244
                      ::|||||::|...:..|..:|||||  :|..   |:|    |..:.|:..|:  |
Mosquito   123 IVHPGLNVRRFKNDIALIKLASNITMTPHVQPICLWTMDNN---QELIVGKNGTVLGFGLTE--Q 182

  Fly   245 TLITSTVKER-----NPADCLNR----YPSFRSASQVCAGGQRKGDTCAGISGSPVMGIMGSGVD 300
            .:::..:|:.     :...||..    :.::.::...|.||:.....|.|.||    |.:...|:
Mosquito   183 DVVSEQLKQASIGVVDTLTCLANDRAAFGTYLTSEMFCGGGRDGVSACNGDSG----GGLFLEVE 243

  Fly   301 EFVFLAGIASY-----GQQYCYSAGIPGVYTKIGHFSEWIKANLAP 341
            ...|:.||.|:     ....|.::... .:..:..:.:||:..:.|
Mosquito   244 GRWFVRGIVSFIPLRKNTALCDTSKFT-AFADVAKYLKWIEQYIDP 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	3/7 (43%)
		Tryp_SPc	108..338	CDD:238113	60/267 (22%)
		Tryp_SPc	108..335	CDD:214473	58/264 (22%)
AgaP_AGAP012270	XP_320269.4	Tryp_SPc	40..284	CDD:238113	60/268 (22%)
		Tryp_SPc	42..282	CDD:214473	58/264 (22%)
		Tryp_SPc	329..>443	CDD:304450
		Tryp_SPc	614..842	CDD:304450
		Tryp_SPc	614..839	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910