DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP009249

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_320028.4	Gene:	AgaP_AGAP009249 / 1280205	VectorBaseID:	AGAP009249	Length:	776	Species:	Anopheles gambiae

Alignment Length:	268	Identity:	72/268 - (26%)
Similarity:	115/268 - (42%)	Gaps:	54/268 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 PVFR---DRGAENAELNEYPWMVL-----------LLYENRLSLIRYVLTAAHCVIGG-YLTQND 151
            |||:   .:.::.:.|....|..:           |::||      ::||:|.|...| |:|
Mosquito    18 PVFQRPHQKMSDFSHLGRIGWTGIDGTVRWNCSGTLVWEN------FILTSARCTTDGKYVT--- 73

  Fly   152 LVLKSVRLGESTTDCITSESRCPHLD-VEVGQTTVHQGFTSSGGTYR---NDIALLRLQFPVRYT 212
              :...|.|:......|.:.....|. ||:.:...|:        :|   :||||:||:..|...
Mosquito    74 --IYVARFGDLDLFNATDDQYAQQLKIVEIIRHPEHR--------HRDRYHDIALMRLERKVVLH 128

  Fly   213 KKIQPICL-LDAEFPLQDLNLQISGWDPT--KSSQTLITSTVKERNPAD--CLNRYPSFRS---- 268
            ..:.|.|| .|.|...:  ..:.:||..|  .:::|.|...|.....|:  |...|.:.|.
Mosquito   129 DTVAPACLWTDDEIRFK--RFEATGWGDTGFAAAKTPILLKVALSPVANEQCNEHYSNLRGLRNG 191

  Fly   269 --ASQVCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHF 331
              |:|:|||..|. |||.|.||.|:...:.....|..||.|:.|:|  ......:|||||::..:
Mosquito   192 LHANQLCAGDARM-DTCPGDSGGPLQVKLLHNTRETPFLVGVTSFG--LACGLSVPGVYTRVAPY 253

  Fly   332 SEWIKANL 339
            ..||::.|
Mosquito   254 VPWIRSVL 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	68/256 (27%)
		Tryp_SPc	108..335	CDD:214473	66/253 (26%)
AgaP_AGAP009249	XP_320028.4	Trypsin	43..257	CDD:278516	64/237 (27%)
		Tryp_SPc	46..260	CDD:238113	66/237 (28%)
		Tryp_SPc	312..552	CDD:304450
		Tryp_SPc	654..>751	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910