DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP009211

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_319989.4	Gene:	AgaP_AGAP009211 / 1280170	VectorBaseID:	AGAP009211	Length:	265	Species:	Anopheles gambiae

Alignment Length:	274	Identity:	81/274 - (29%)
Similarity:	118/274 - (43%)	Gaps:	42/274 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 CGQTTPVFRDRGAENAELNEYPWMVLLLYENRL--------SLI--RYVLTAAHCVIGGYLTQND 151
            ||.|.......| :.|....:|||.||  |..:        |||  |::|||||||.......:|
Mosquito     1 CGVTRVQLIAYG-QPARAYAFPWMALL--ETSVSDDLPCGGSLISDRHILTAAHCVKARKRDCDD 62

  Fly   152 LV-LKSVRL--GES-TTDCITSESRC--PHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVR 210
            .: .|....  ||| ..|.....:.|  |...:.:.....|..:  |..:.|||:|::|||:|..
Mosquito    63 RIHFKDDEYDSGESEEADGAEYSASCGPPAQRIPIETIVTHPKY--SARSKRNDLAIIRLQYPAI 125

  Fly   211 YTKKIQPICL-----LDAEFPLQDLNLQISGWDPTKSSQ--TLITSTVKERNP-ADCLNRYPSF- 266
            ....:.||||     |.|..|....   ::||..|::.|  .::...:....| .||..|....
Mosquito   126 IGYNVIPICLPLTEQLRAYRPADSF---VTGWGLTETGQRSAVLRYAILPALPLPDCAMRIKELD 187

  Fly   267 ----RSASQVCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTK 327
                .....:||||..:...|.|.||.|:..:..|  ..|| |.|:.|:|.:.|.:...|||:..
Mosquito   188 RIIVLDDGHLCAGGNNRTAHCHGDSGGPLQYVSDS--TRFV-LQGVVSFGVKTCGTKIAPGVFAN 249

  Fly   328 IGHFSEWI--KANL 339
            :.||.:||  :||:
Mosquito   250 VTHFIDWIVQEANV 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	76/260 (29%)
		Tryp_SPc	108..335	CDD:214473	74/255 (29%)
AgaP_AGAP009211	XP_319989.4	Tryp_SPc	9..257	CDD:214473	74/258 (29%)
AgaP_AGAP009211	XP_319989.4	Tryp_SPc	9..257	CDD:238113	74/258 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920