DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and TRY6_ANOGA

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_317175.2	Gene:	TRY6_ANOGA / 1277692	VectorBaseID:	AGAP008290	Length:	273	Species:	Anopheles gambiae

Alignment Length:	264	Identity:	72/264 - (27%)
Similarity:	118/264 - (44%)	Gaps:	53/264 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 TTPVF----------RDRGAENAELNEYPWMVLLLYENRL----SLI--RYVLTAAHCVIGGYLT 148
            |.|.|          |..|....::::.|:.:.|.|..:.    |::  :::||||||:
Mosquito    31 TRPAFHPNAPYLAGKRIVGGFVIDISDAPYQISLQYNGKHHCGGSILNSKWILTAAHCI------ 89

  Fly   149 QNDL---VLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVR 210
              ||   |..:||:|       :||.......:.:.:...|.|.:|.|..|  |||||.|:..:.
Mosquito    90 --DLYSEVKPTVRVG-------SSEHAAGGTVLHLLRIVPHPGHSSGGNNY--DIALLELECELT 143

  Fly   211 YTKKIQPICLLDAEFPLQDLNLQI-SGWDPTKS----SQTLITSTVKERNPADCLNRYPSFRSAS 270
            :...:||:.|.:.:.|:.:..:.| |||..|.|    :..|..:.|...|..:|...|.|:...:
Mosquito   144 FNDNVQPVQLPEQDDPIDEGTMGIVSGWGMTMSAADLNAILRATNVPTVNQQECNQAYQSYGGVA 208

  Fly   271 Q--VCAGGQRKG-DTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFS 332
            :  .|||.::.| .||...||.|   .:..|.     |.|:.|:..: |..||.||||.::....
Mosquito   209 EQMFCAGYKQGGTGTCRNDSGGP---FVAEGK-----LIGVVSWSHE-CALAGYPGVYARVASVR 264

  Fly   333 EWIK 336
            :||:
Mosquito   265 DWIR 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	68/246 (28%)
		Tryp_SPc	108..335	CDD:214473	66/243 (27%)
TRY6_ANOGA	XP_317175.2	Tryp_SPc	46..267	CDD:214473	67/246 (27%)
TRY6_ANOGA	XP_317175.2	Tryp_SPc	47..270	CDD:238113	68/248 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910