DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP008403

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_317049.4	Gene:	AgaP_AGAP008403 / 1277577	VectorBaseID:	AGAP008403	Length:	873	Species:	Anopheles gambiae

Alignment Length:	236	Identity:	70/236 - (29%)
Similarity:	102/236 - (43%)	Gaps:	45/236 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 LLYENRLSLIRYVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCITSESRCPHLD-VEVGQTTVH 186
            |::||      ||||||||.    ...|:.....||||:...|..:.:.....|. ||:.:...|
Mosquito    51 LIWEN------YVLTAAHCT----ADDNNAAPDVVRLGDINLDDDSDDKYAQQLKIVEIIRHPEH 105

  Fly   187 QGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLL-DAEFPLQDLNLQISGWDPTKSSQTLITST 250
            : |:|.    .:|:|||||:..|.....:.|.||. |.|.|..  :::.:||..|..::|.|...
Mosquito   106 R-FSSR----YHDLALLRLERNVTLHDTVAPGCLWNDEEIPFP--SMEATGWGSTGFAKTPILLK 163

  Fly   251 VK----------------ERNPADCLNRYPSFRSASQVCAGGQRKGDTCAGISGSPVMGIMGSGV 299
            |.                :|.....|..|       |:|| |..|.|||.|.||.|:...:.:..
Mosquito   164 VSLSLVPKSTCDQQYRKGDRGLRQGLQDY-------QLCA-GDIKMDTCPGDSGGPLQMKLLANA 220

  Fly   300 DEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANLA 340
            ....|:..:.|:| ..| ....||||.|:..:..||::.||
Mosquito   221 KMTPFIIAVTSFG-SVC-GQSTPGVYMKVSPYIPWIRSELA 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	68/232 (29%)
		Tryp_SPc	108..335	CDD:214473	66/229 (29%)
AgaP_AGAP008403	XP_317049.4	Tryp_SPc	20..256	CDD:238113	68/231 (29%)
		Tryp_SPc	20..254	CDD:214473	66/229 (29%)
		Tryp_SPc	324..552	CDD:304450
		CLIP	577..617	CDD:295450
		Tryp_SPc	656..872	CDD:304450
		Tryp_SPc	656..869	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910