DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP005196

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_314095.2	Gene:	AgaP_AGAP005196 / 1274902	VectorBaseID:	AGAP005196	Length:	264	Species:	Anopheles gambiae

Alignment Length:	253	Identity:	70/253 - (27%)
Similarity:	112/253 - (44%)	Gaps:	50/253 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 GAENAELNEYPWMVLLLYENRL-----SLI--RYVLTAAHCVIGGYLTQNDLVLKSVRLGESTTD 165
            |..:.|..:.|::..|:|.|..     |:|  |::|||||||....:|.    |..||:|  |.|
Mosquito    37 GGTDVEDGKAPYLAGLVYNNSATYCGGSIIAARWILTAAHCVTNVNVTN----LTVVRVG--TND 95

  Fly   166 CITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEFPLQDL 230
            .....|.     .::.:...|:.:  |..|:|||:|||||:.|:::.:.::.|.|.:...|: :.
Mosquito    96 NYEGGSM-----YQIDRVIPHERY--SAITFRNDVALLRLKTPIKFEEHVEKIELNEELVPI-NA 152

  Fly   231 NLQISGW--------DPTKSSQTLITSTVKERNPADCLNRYPSFRSASQV-----CAGGQRKGDT 282
            .|.|.||        :|.:      |..:|.::..  |||.....:.|.:     |...:.....
Mosquito   153 TLTIVGWGFVGWNKENPKR------TQVIKVQHIG--LNRCRKMANGSAIYPEHLCTFSRAGHGP 209

  Fly   283 CAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANLA 340
            |.|.|||||:. .|..|       |:.|:......:.|:|.|...|.:|..||...:|
Mosquito   210 CKGDSGSPVVW-KGKQV-------GVVSWAMAGVCAIGLPDVQASIRYFYGWITKTMA 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	69/249 (28%)
		Tryp_SPc	108..335	CDD:214473	67/246 (27%)
AgaP_AGAP005196	XP_314095.2	Tryp_SPc	35..257	CDD:238113	69/249 (28%)
AgaP_AGAP005196	XP_314095.2	Tryp_SPc	35..254	CDD:214473	67/246 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910