DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18754 and AgaP_AGAP003686

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_313469.4	Gene:	AgaP_AGAP003686 / 1274361	VectorBaseID:	AGAP003686	Length:	368	Species:	Anopheles gambiae

Alignment Length:	389	Identity:	98/389 - (25%)
Similarity:	147/389 - (37%)	Gaps:	111/389 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LSSC----QKDEKCTRLVSCSPLMNILR---PRGMTQAEKDV-FAHRQCGLDPNGHELLHMVYVC 83
            |::|    .:...|..|..|.|:..:||   .||.|....:. |........|.|....|   ||
Mosquito    13 LTACSTVINRPGYCVPLAQCGPVARLLRLISTRGTTATPDEARFLRASICPTPEGATGYH---VC 74

  Fly    84 C------------------------PELGDVL--PN-----KQTCGQTTPVFRDRGAENAELNEY 117
            |                        |....::  ||     :..||....|.:....:.|.|.:|
Mosquito    75 CDVTAVQTTTTPAPTTQPPTTVAAAPATASLVNHPNIRLFDRTNCGLPGTVNKIAFGQQARLFQY 139

  Fly   118 PWMVLLLYENR------------LSLIRYVLTAAHCVIGGYLTQNDLVLKSVRLGESTT----DC 166
            |||.:::|.:.            :..:||||||||| |.|.:.:    ::.||:||..|    ||
Mosquito   140 PWMAMIVYVSNTTGTESSECAGTIINVRYVLTAAHC-IDGQMER----MRYVRIGEYDTRTDPDC 199

  Fly   167 ITSESRCPHLDVEVGQTTVHQGFT---SSGGTYRNDIALLRLQFPVRYTK-KIQPICLLDAEFPL 227
            .......|.....|.....|..||   .||    :||.||||...:.::. .:.|:||
Mosquito   200 EEDTCAAPIQRYGVEDAIFHPNFTRIVRSG----HDIGLLRLNRSIDFSSGDVSPVCL------- 253

  Fly   228 QDLNLQISGWDPT-------------KSSQTLITSTVKERNPADC-LNRYPSFRSASQVCAGGQR 278
             .....:.|:|||             :.|..|:.:.:.   |..| |:.|       .:|||...
Mosquito   254 -PFTTGLMGFDPTLYWITGWGLTERLEVSPVLLQARIP---PVSCSLSSY-------AICAGFGN 307

  Fly   279 KGDTCAGISGSPVMGIMGSGVDEFVF---LAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANL 339
            ....|.|.||.|    |.:.|.|:.|   ..|:.|.|.: |.:.|:||:.:::..|.:||..|:
Mosquito   308 ATLHCEGDSGGP----MKAQVPEYNFRFVQYGVISAGPR-CGTQGVPGISSRVSFFMQWILDNI 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	14/52 (27%)
		Tryp_SPc	108..338	CDD:238113	73/266 (27%)
		Tryp_SPc	108..335	CDD:214473	71/263 (27%)
AgaP_AGAP003686	XP_313469.4	CLIP	16..75	CDD:288855	15/61 (25%)
		Tryp_SPc	131..362	CDD:214473	71/262 (27%)
		Tryp_SPc	131..362	CDD:238113	71/262 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24260
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020