DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP004149

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_313033.3	Gene:	AgaP_AGAP004149 / 1273976	VectorBaseID:	AGAP004149	Length:	543	Species:	Anopheles gambiae

Alignment Length:	357	Identity:	110/357 - (30%)
Similarity:	156/357 - (43%)	Gaps:	64/357 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LAECVRLSSCQKDEKCTRLVSCSPLMNILRPRGMTQAEKDVFAHRQCGLDPNGHELLHMVYVCCP 85
            :|..:|.::.|......||...:||.....|:..|.|            .|...|||..|
Mosquito   211 VAPVMRTTTRQPVLGSNRLAETTPLPTTEPPQPPTTA------------IPTTTELLTTV----- 258

  Fly    86 ELGDVLP-----NKQTCGQTTPVFRDRGAENAELNEYPWMVLLLYENRL----------SLI--R 133
             |..|:|     |...||.:... |..|.|.....::|||..|.|.|:.          |||  |
Mosquito   259 -LPTVVPDQPMINAPLCGLSVNT-RIIGGETEVPGQFPWMARLAYRNQTSGRVTYRCAGSLITNR 321

  Fly   134 YVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCITSESRCP--HLDVEVGQTTVHQGFTSSGGTY 196
            :|:|.||||..   ..::|.|.|:|||:...:.:| :.||.  :.|..:.|...|:.:...  .|
Mosquito   322 HVITVAHCVTN---LIDELQLVSIRLGDLECNAVT-DPRCSARYQDFAIEQIIPHESYDVP--KY 380

  Fly   197 RNDIALLRLQFPVRYTKKIQPICLLDAEFPLQDLNLQ-----ISGWDPTKSSQTLITSTVK-ERN 255
            .|||||::|:........|.|:||...::....|||.     |:||..|.:.....:.|:: .|.
Mosquito   381 ANDIALIKLRETTETYNIISPLCLPTDQYAPYALNLTGQLGIIAGWGSTSNRSNTPSPTLQWLRL 445

  Fly   256 P----ADCLNRY---------PSFRSASQVCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAG 307
            |    |.|.|.|         |...|.:|:||.||...|.|.|.||.|:|....|..|.||.| |
Mosquito   446 PIVDTAGCANAYARYSVNSRNPIIVSGNQMCAQGQENRDACQGDSGGPLMNEAISTRDRFVLL-G 509

  Fly   308 IASYGQQYCYSAGIPGVYTKIGHFSEWIKANL 339
            :.|:|.:.|..:..|||||:|..:.:||.||:
Mosquito   510 LVSFGPRTCGVSNFPGVYTRISAYIDWILANV 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	12/48 (25%)
		Tryp_SPc	108..338	CDD:238113	86/262 (33%)
		Tryp_SPc	108..335	CDD:214473	84/259 (32%)
AgaP_AGAP004149	XP_313033.3	CLIP	47..92	CDD:288855
		Tryp_SPc	281..537	CDD:214473	85/262 (32%)
		Tryp_SPc	282..537	CDD:238113	84/261 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920