DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CLIPD6

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_312099.2	Gene:	CLIPD6 / 1273147	VectorBaseID:	AGAP002813	Length:	484	Species:	Anopheles gambiae

Alignment Length:	401	Identity:	110/401 - (27%)
Similarity:	164/401 - (40%)	Gaps:	113/401 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 AECVRLSSCQKDEKCTRLVSCSPLMN--ILRPRGMTQAEKDVFAHRQCG-LDPNGHELLHMVYVC 83
            |:|:  ....::..|..:.||..::|  :.|.|.....:....::..|. :.||         ||
Mosquito   112 ADCI--GPDNREGYCINIRSCPDVLNEFVQRQRDPQYVQYIRQSNAVCNYIQPN---------VC 165

  Fly    84 CPELGDVLPNKQT--------------------------------------------CGQTTPVF 104
            ||......|...|                                            ||.:| |.
Mosquito   166 CPLQKSAPPAPPTAPPTAPPTAPPTAPPPPPPAPVTQAPPAPAPSSGPAELLTPETGCGYST-VQ 229

  Fly   105 RDR--GAENAELNEYPWMVLLLYENRL---------SLI--RYVLTAAHCVIGGYLTQNDLVLKS 156
            .:|  |...||||.:|||.|:.|:|.|         |||  |:|||||||:      :.|  |.|
Mosquito   230 HNRVVGGVPAELNGWPWMALVGYKNTLGEVSFKCGGSLITKRHVLTAAHCI------RRD--LSS 286

  Fly   157 VRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLL 221
            |||||..|   ::::...|:||.|.:...|..:....|  ..|:|:|.::|.|:::..|:||||
Mosquito   287 VRLGEHDT---STDAETKHIDVPVVRYESHPSYDKKDG--HTDLAVLYMEFEVQFSDAIKPICL- 345

  Fly   222 DAEFPLQDLNLQ---------ISGWDPT----KSSQTLITSTVKERNPADCLNRYPSF-RSASQ- 271
                ||.:....         ::||..|    ||:..|....:......:|...|... :..||
Mosquito   346 ----PLSETIRSKNFIGYTPFVAGWGRTQEGGKSANVLQELQIPIIANDECRTLYDKIGKVFSQK 406

  Fly   272 ------VCAGGQRKG-DTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIG 329
                  :|||....| |:|.|.||.|:|.....|.:.:.:..||.|||.. |..|.:|||||::.
Mosquito   407 QFDNAVMCAGVIEGGKDSCQGDSGGPLMLPQRFGTEFYYYQVGIVSYGIG-CARAEVPGVYTRVA 470

  Fly   330 HFSEWIKANLA 340
            .|.:||:..:|
Mosquito   471 SFVDWIQQKVA 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	10/51 (20%)
		Tryp_SPc	108..338	CDD:238113	87/262 (33%)
		Tryp_SPc	108..335	CDD:214473	85/259 (33%)
CLIPD6	XP_312099.2	CLIP	25..80	CDD:288855
		CLIP	114..166	CDD:288855	11/62 (18%)
		Tryp_SPc	232..476	CDD:214473	86/262 (33%)
		Tryp_SPc	233..479	CDD:238113	87/264 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920