DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP010730

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_311444.4	Gene:	AgaP_AGAP010730 / 1272531	VectorBaseID:	AGAP010730	Length:	256	Species:	Anopheles gambiae

Alignment Length:	248	Identity:	69/248 - (27%)
Similarity:	107/248 - (43%)	Gaps:	35/248 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 EYPWMVLLLYENRLSLIRYVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCI----------TSE 170
            ||||:|.:     |:|.:....:...|.||.|..:.||:.:....:..||.:          |.|
Mosquito     7 EYPWVVYI-----LALKKQEANSGDFVCGGTLIHSRLVVTTAHNTDGKTDLVARFGEWDISTTKE 66

  Fly   171 ---SRC--PHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEFPLQDL 230
               .:|  ||.|::|.:...|..:..:  ..:||||||.|...|:|...|:||||..........
Mosquito    67 PFPQQCLFPHQDIDVAEVIKHPQYVFN--PIQNDIALLVLAENVQYAAHIRPICLPQPTDEFVGQ 129

  Fly   231 NLQISGWDPTKS--SQTLITSTVKERNPADC--LNRYPS---FRSASQ--VCAGGQRKGDTCAGI 286
            ....:||...:.  :..:...|:.....|:|  :.||..   |.:..:  :||||:...|.|.|.
Mosquito   130 RCVSNGWGKERGVYANVMKKLTLPVIGRANCTRMLRYAGLGPFYTLREGFLCAGGEVAVDMCKGD 194

  Fly   287 SGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANL 339
            .|||:.....||.   ..||||.|:|.. |.....||||..:..:.:|:..::
Mosquito   195 GGSPLACQTESGT---YVLAGIVSWGIG-CGGFNTPGVYVAVNRYVQWLNEHI 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	69/245 (28%)
		Tryp_SPc	108..335	CDD:214473	68/242 (28%)
AgaP_AGAP010730	XP_311444.4	Tryp_SPc	7..242	CDD:238113	69/245 (28%)
AgaP_AGAP010730	XP_311444.4	Tryp_SPc	7..238	CDD:214473	68/241 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910