DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and Ctrl

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_446461.1	Gene:	Ctrl / 117184	RGDID:	621501	Length:	264	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	77/270 - (28%)
Similarity:	115/270 - (42%)	Gaps:	52/270 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 CG--QTTPVF----RDRGAENAELNEYPWMVLLLYENRL-----SLI--RYVLTAAHCVI--GGY 146
            ||  ..||..    |....|||....:||.|.|......     |||  .:|:|||||.:  |.:
  Rat    19 CGVPAITPALSYNQRIVNGENAVPGSWPWQVSLQDNTGFHFCGGSLIAPNWVVTAAHCKVTPGRH 83

  Fly   147 LTQNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRY 211
            .         |.|||..    .|.:..|...:.:.:...|..:..:  |..||:.||:|..|.||
  Rat    84 F---------VILGEYD----RSSNAEPIQVLSISKAITHPSWNPN--TMNNDLTLLKLASPARY 133

  Fly   212 TKKIQPICLLDAEFPL-QDLNLQISGW---------DPTKSSQTLI-TSTVKERNPADCLNRYPS 265
            |.::.|:||..:...| ..|....:||         .|.:..|.:: ..||.:     |...:.|
  Rat   134 TAQVSPVCLASSNEALPAGLTCVTTGWGRISGVGNVTPARLQQVVLPLVTVNQ-----CRQYWGS 193

  Fly   266 FRSASQVCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGH 330
            ..:.|.:|||| ....:|.|.||.|::...|   :.:| |.||.|:|.:.| :...|.:||::..
  Rat   194 RITDSMICAGG-AGASSCQGDSGGPLVCQKG---NTWV-LIGIVSWGTENC-NVQAPAMYTRVSK 252

  Fly   331 FSEWIKANLA 340
            |:.||...:|
  Rat   253 FNTWINQVIA 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	71/249 (29%)
		Tryp_SPc	108..335	CDD:214473	69/246 (28%)
Ctrl	NP_446461.1	Tryp_SPc	33..257	CDD:214473	70/249 (28%)
Ctrl	NP_446461.1	Tryp_SPc	34..260	CDD:238113	71/251 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910