DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18754 and St14

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_446087.1	Gene:	St14 / 114093	RGDID:	69288	Length:	855	Species:	Rattus norvegicus

Alignment Length:	266	Identity:	79/266 - (29%)
Similarity:	117/266 - (43%)	Gaps:	45/266 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 CG--QTTPVFRDRGAENAELNEYPWMVLL--LYENRL---SLIR--YVLTAAHCVIGGYLTQNDL 152
            ||  ..|...|..|..||:..|:||.|.|  |.:..|   |||.  ::::||||.      |::.
  Rat   604 CGLRSFTKQARVVGGTNADEGEWPWQVSLHALGQGHLCGASLISPDWLVSAAHCF------QDET 662

  Fly   153 VLK-------SVRLGESTTDCITSESRCPHLDVE---VGQTTVHQGFTSSGGTYRNDIALLRLQF 207
            :.|       :..||      :..:|:.....|:   :.:...|..|...  |:..|||||.|:.
  Rat   663 IFKYSDHTMWTAFLG------LLDQSKRSASGVQEHKLKRIITHPSFNDF--TFDYDIALLELEK 719

  Fly   208 PVRYTKKIQPICLLDAE--FPLQDLNLQISGWDPTKSSQT----LITSTVKERNPADCLNRYPSF 266
            |..|:..::||||.|..  ||.... :.::||..||...|    |....::..|...|....|..
  Rat   720 PAEYSTVVRPICLPDNTHVFPAGKA-IWVTGWGHTKEGGTGALILQKGEIRVINQTTCEELLPQQ 783

  Fly   267 RSASQVCAGGQRKG-DTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGH 330
            .:...:|.|....| |:|.|.||.|:..:...|   .:|.||:.|:|:. |.....|||||:|..
  Rat   784 ITPRMMCVGFLSGGVDSCQGDSGGPLSSVEKDG---RIFQAGVVSWGEG-CAQRNKPGVYTRIPE 844

  Fly   331 FSEWIK 336
            ..:|||
  Rat   845 VRDWIK 850

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	75/253 (30%)
		Tryp_SPc	108..335	CDD:214473	72/250 (29%)
St14	NP_446087.1	SEA	88..178	CDD:396113
		CUB	214..332	CDD:238001
		CUB	340..444	CDD:238001
		LDLa	454..486	CDD:238060
		LDLa	492..523	CDD:238060
		LDLa	525..559	CDD:238060
		LDLa	567..602	CDD:238060
		Tryp_SPc	615..852	CDD:238113	75/255 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910