DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP013252

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_003436670.1	Gene:	AgaP_AGAP013252 / 11175997	VectorBaseID:	AGAP013252	Length:	597	Species:	Anopheles gambiae

Alignment Length:	299	Identity:	75/299 - (25%)
Similarity:	125/299 - (41%)	Gaps:	65/299 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 PELGDVLP-----NKQTCGQTTPVFRDRGAENAELNEYPWMVLL----------LYENRLSLIR- 133
            |.|.|..|     |..||| .:|..  .||.::.| .:||:.|:          :....::||.
Mosquito   302 PLLVDNSPKLRMLNFNTCG-ISPYM--TGANDSFL-AFPWIGLVEMVAPGQGKTMAVCHVTLISE 362

  Fly   134 -YVLTAAHCVIGGYLTQNDLVLKSVRLG--ESTT--DCITSESR--C--PHLDVEVGQTTVHQGF 189
             |.:..|||.      .||.:.:::|.|  :.||  |||.....  |  |...:.:.:..|...|
Mosquito   363 WYAVGPAHCF------SNDGMERTLRFGDYDKTTDKDCIERNGTLVCAPPVQILPIERVIVRPDF 421

  Fly   190 TSSGGTYRNDIALLRLQFPVRYTK-KIQPICLLDAEFPLQDLNLQISGWDPTK--------SSQT 245
            .....|  :||||:.|:.|...:: .::||||        .:.:.:..:.||.        ....
Mosquito   422 DRQAIT--DDIALIELRRPANISQPNVKPICL--------PVTVDLRSYKPTSFTLGGFPAQGNR 476

  Fly   246 LITSTVKERNPADCLNR-----YPSFRSASQVCA----GGQRKGDTCAG-ISGSPVMGIMGSGVD 300
            ::.|.....|..:|..|     ||..:|.:|:||    ....:.:.|.. :|||.:..:...|..
Mosquito   477 VVASRPTYLNSVNCQERYNAIYYPLRKSHTQICAVAEVSSTNRTEPCERMLSGSVLQTVQQLGRR 541

  Fly   301 EFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANL 339
            :..||.|:.|:|.:.| .|.:|.:||.:..:.:||..|:
Mosquito   542 DRYFLQGLLSFGAREC-DATVPDIYTNVPIYLDWILYNM 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	65/268 (24%)
		Tryp_SPc	108..335	CDD:214473	63/265 (24%)
AgaP_AGAP013252	XP_003436670.1	Tryp_SPc	47..287	CDD:214473
		Tryp_SPc	48..287	CDD:238113
		Tryp_SPc	334..575	CDD:214473	60/257 (23%)
		Tryp_SPc	335..575	CDD:304450	60/256 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910