DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP013089

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_003436251.1	Gene:	AgaP_AGAP013089 / 11175918	VectorBaseID:	AGAP013089	Length:	634	Species:	Anopheles gambiae

Alignment Length:	290	Identity:	87/290 - (30%)
Similarity:	129/290 - (44%)	Gaps:	61/290 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 LPNKQT--CGQTTPVF-RDRGAENAELNEYPWMVLLLYEN---------------RLSLIRYVLT 137
            ||....  ||.:.... |..|..:|:||.:|||..|.|.:               .|....:|||
Mosquito   363 LPTNDVDRCGMSNGTHTRVVGGVDAQLNAWPWMAALGYRSTSFELNAGPRFLCGGTLITTLHVLT 427

  Fly   138 AAHCVIGGYLTQNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIAL 202
            .|||:        ...|..|||||  .|..:.:.....:|:.:.:..||:.:...  ...|||||
Mosquito   428 VAHCI--------QTALYFVRLGE--LDITSDQDGANPVDIYIQRWVVHERYDEK--KIYNDIAL 480

  Fly   203 LRLQFPVRYTKKIQPICL-LDAEFPLQDLNLQ---ISGW------DPT----KSSQTLITSTVKE 253
            :.||..|..|:.::|||| ::|:...:||...   |:||      .||    :.:|.::.
Mosquito   481 VLLQKSVTITEAVRPICLPVEAKQRTKDLTYYAPFIAGWGAVGYNGPTAARLQEAQVVVL----- 540

  Fly   254 RNPAD-CLNRYPSFRSA-----SQVCAGGQRKG-DTCAGISGSPVM--GIMGSGVDEFVFLAGIA 309
              |.| |...|..:...     :.:|||..:.| |:|.|.||.|:|  .:..:|...:..|.|:.
Mosquito   541 --PVDQCAFNYKLYFPGQIFDDTVLCAGFPQGGKDSCQGDSGGPLMLPELSSNGQYYYYTLIGLI 603

  Fly   310 SYGQQYCYSAGIPGVYTKIGHFSEWIKANL 339
            |||.: |..||.||||.|:..:..||:|||
Mosquito   604 SYGYE-CARAGFPGVYVKVTAYLPWIEANL 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	79/267 (30%)
		Tryp_SPc	108..335	CDD:214473	77/264 (29%)
AgaP_AGAP013089	XP_003436251.1	CLIP	250..304	CDD:288855
		Tryp_SPc	380..628	CDD:214473	78/267 (29%)
		Tryp_SPc	381..631	CDD:238113	79/269 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920