DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and tmprss2.12

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_031752400.1	Gene:	tmprss2.12 / 100497514	XenbaseID:	XB-GENE-22065925	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	258	Identity:	74/258 - (28%)
Similarity:	119/258 - (46%)	Gaps:	38/258 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 CGQTT-PVFRDRGAENAELNEYPWMVLLLYEN------RLSLIRYVLTAAHCVIGGYLTQNDLVL 154
            ||.:| ...|..|..:|.:.::||.|.|.|::      .:....:::||||||.|.        .
Frog   251 CGLSTYGESRIVGGSSASIGDWPWQVNLQYDDTNLCGGSVIAANWIVTAAHCVQGD--------T 307

  Fly   155 KSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPIC 219
            .|..|.::....|...|........|.:..||..::|.  |..|||||::|:..:.::...:|:|
Frog   308 SSPSLWKAFIGKIKMPSYYDSSAYSVDRIIVHPDYSSQ--TNSNDIALMKLKTSIAFSSISRPVC 370

  Fly   220 LLDAEFPLQDLNLQ---ISGWDPTKSSQTLITSTVKER-----NPADCLNR---YPSFRSASQVC 273
            |  ..:.:|....|   ||||. |.|.:..|:|.:|..     :|..| |:   |....::|.:|
Frog   371 L--PNYGMQWEEGQPCYISGWG-TTSQKGSISSVLKYAMVPLISPTTC-NQTIMYNGAITSSMIC 431

  Fly   274 AGGQRKG-DTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWI 335
            ||..:.| |:|.|.||.|::    :..:...:|.|..|:|.. |.:...||||..:..|.:||
Frog   432 AGYPKGGVDSCQGDSGGPLV----TKTNSLWWLVGDTSWGDG-CANVYRPGVYGNMTVFLQWI 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	70/246 (28%)
		Tryp_SPc	108..335	CDD:214473	68/244 (28%)
tmprss2.12	XP_031752400.1	LDLa	127..155	CDD:238060
		SRCR_2	160..255	CDD:406055	2/3 (67%)
		Tryp_SPc	261..489	CDD:238113	68/246 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910