DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and tmprss15

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_031752048.1	Gene:	tmprss15 / 100490249	XenbaseID:	XB-GENE-999987	Length:	994	Species:	Xenopus tropicalis

Alignment Length:	387	Identity:	100/387 - (25%)
Similarity:	157/387 - (40%)	Gaps:	98/387 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 ECV-RLSSCQK--------DEK-CTRLVSCSPLMNILRPRGMTQAEKDVFAHRQCGLDPNGHELL 77
            ||: ..:.|.|        ||: |.||.:.|       ..|:.|.:.....|..| :|....::.
Frog   631 ECIPNTAVCDKHRDCDDGTDERHCVRLFNSS-------MSGLVQFKVQSEWHTAC-IDHWNEDIS 687

  Fly    78 HMVYVCCPELG-----------------------------DVLPNKQTCGQT------------- 100
            :.:   |..||                             .:||:.|...|:
Frog   688 NDI---CHRLGLGNVNLTSAVLSEGNGPFVTLIQVEDGSLSLLPSDQCANQSVIHIQCQQRECGK 749

  Fly   101 --TPV---FRDRGAENAELNEYPWMVLLLYENR----LSLI--RYVLTAAHCVIGGYLTQNDLVL 154
              .|:   .:..|..:|.|..:||:|.|.|.:|    .||:  .::::|||||.|..|..::.
Frog   750 RLVPIKSGSKIVGGSDAALGAWPWIVSLYYNDRQTCGASLVNQEWLVSAAHCVYGRNLIPSNW-- 812

  Fly   155 KSVRLGESTTDCITSESRCPHLDVE-VGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPI 218
             ..|||..|...:|.    |.:..: :.|..::..:...  |..:||.::.|||.|.|:..||||
Frog   813 -KARLGLHTNLNLTQ----PQIATQMIDQIVINPQYNRR--TKDSDIVMMHLQFKVNYSDYIQPI 870

  Fly   219 CL--LDAEFPLQDLNLQISGWDPTKSSQTLITSTVKERNPA----DCLNRYPSFRSASQVCAGGQ 277
            ||  .|.||.: .:|..|:||..|:|...:.....:...|.    .|..:.|.:.....:..||.
Frog   871 CLPETDQEFSV-GINCSIAGWGRTQSGGPVPNILQEAEIPLISNHKCQQQMPEYNITDNMVCGGY 934

  Fly   278 RKG--DTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKA 337
            .:|  |||.|.||.|:|....   :|: ||.|:.|:|.. |.....||||.::..|:.|||:
Frog   935 EEGGIDTCQGDSGGPMMCQQN---NEW-FLVGVTSFGYG-CAQPSRPGVYVRVTEFTNWIKS 991

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	9/49 (18%)
		Tryp_SPc	108..338	CDD:238113	77/245 (31%)
		Tryp_SPc	108..335	CDD:214473	74/241 (31%)
tmprss15	XP_031752048.1	SEA	36..>103	CDD:396113
		LDLa	157..190	CDD:197566
		CUB	199..305	CDD:238001
		MAM	321..478	CDD:395504
		CUB	501..608	CDD:395345
		LDLa	620..654	CDD:238060	6/22 (27%)
		SR	655..746	CDD:214555	15/101 (15%)
		Tryp_SPc	760..991	CDD:238113	76/245 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910