DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and tmprss9

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_002940084.3	Gene:	tmprss9 / 100489279	XenbaseID:	XB-GENE-993973	Length:	1151	Species:	Xenopus tropicalis

Alignment Length:	346	Identity:	99/346 - (28%)
Similarity:	140/346 - (40%)	Gaps:	67/346 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SSCQKDEKCTRLVSCSP-LMNILRPRGMTQ------AEKDVFAHRQCGLDPNGHELLHMVYVCCP 85
            |:.:...|.|.....|| .:.|..|...||      |.....::|.|...||            |
Frog   837 STTKYTSKRTTTAKTSPTALRITEPARSTQRPVPCSASTYKCSNRVCISKPN------------P 889

  Fly    86 ELGDVL-----PNKQTC----GQTTPVFRDRGAENAELNEYPWMVLLLY---ENRLSLI----RY 134
            |...:.     .::|.|    ....|..:..|...:...|:||.|.|..   |::...:    |:
Frog   890 ECDGIQDCNNGSDEQNCDCGFAPVLPFNKIVGGSGSVRGEWPWQVSLWLRRKEHKCGAVLISDRW 954

  Fly   135 VLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQT----TVHQGFTSSGGT 195
            :|:||||    :...:|..|.:..||            .|.|:...|:.    .:|:....:..|
Frog   955 LLSAAHC----FDIYSDPKLWAAYLG------------TPFLNGVEGRVEKIFRIHKHPFYNVYT 1003

  Fly   196 YRNDIALLRLQFPVRYTKKIQPICLLDAE--FPLQDLNLQISGWDPTKS----SQTLITSTVKER 254
            ..||:|||.|..|:.||..|:||||.|..  || :.....|:||..||.    |:.|..::|...
Frog  1004 LDNDVALLELPSPLTYTNLIRPICLPDISHIFP-EGTRCFITGWGSTKEGGAMSRQLQKASVSIV 1067

  Fly   255 NPADCLNRYPSFRSASQVCAGGQRKG-DTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYS 318
            ....|...||...|...:|||..:.| |:|:|.:|.|:.....||   ..|||||.|:|.. |..
Frog  1068 GDQTCKKFYPIQISPRMLCAGFMQGGVDSCSGDAGGPLACREPSG---RWFLAGITSWGYG-CAR 1128

  Fly   319 AGIPGVYTKIGHFSEWIKANL 339
            ...|||||:|.....||..||
Frog  1129 PYFPGVYTRITSVRNWIGQNL 1149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	13/55 (24%)
		Tryp_SPc	108..338	CDD:238113	78/247 (32%)
		Tryp_SPc	108..335	CDD:214473	76/244 (31%)
tmprss9	XP_002940084.3	SEA	60..156	CDD:396113
		LDLa	186..221	CDD:238060
		Tryp_SPc	234..463	CDD:214473
		Tryp_SPc	547..774	CDD:238113
		LDLa	871..906	CDD:238060	8/46 (17%)
		Tryp_SPc	919..1145	CDD:238113	76/246 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910