DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and proc.2

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001120289.1	Gene:	proc.2 / 100145345	XenbaseID:	XB-GENE-5882297	Length:	681	Species:	Xenopus tropicalis

Alignment Length:	321	Identity:	83/321 - (25%)
Similarity:	123/321 - (38%)	Gaps:	95/321 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 TQAEKDVFA--HRQCGLDPNGHELLHMVYVCCPELGDVLPNKQTCGQTTPVFRDRGAENAELNEY 117
            |...|.|:.  |....::|:.:.        .|: |||              |..|....||.:.
Frog   406 TGTSKSVWEENHGLASVEPDDYN--------TPD-GDV--------------RIVGGMRCELGQC 447

  Fly   118 PWMVLLLYENR------LSLI--RYVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCITSESRCP 174
            ||.| |:..||      .|||  |:||:||||.                           ||:.|
Frog   448 PWQV-LIRNNRGFGFCGGSLISSRWVLSAAHCF---------------------------ESQIP 484

  Fly   175 H-------------LD---VEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICL--- 220
            |             :|   :.|.|...|..:.:.  .|.:|||||.|:.|..:.:..:||||
Frog   485 HHVTIGDYDTYRRDMDEQKIAVLQVFSHPNYLAE--FYDHDIALLFLRSPAMFGEYSRPICLPNP 547

  Fly   221 -LDAEFPLQDLNLQISGWDPTKSSQTLITSTVKERNP----ADCLNRYPSFRSASQVCAGGQRKG 280
             |......:....|:|||..|:.........:|.|.|    ..|:....:..:.:..|| |.::|
Frog   548 GLGKMLTQEGQTGQVSGWGATRQFGPYTRFLLKVRLPIVSQETCMASTENILTGNMFCA-GYKEG 611

  Fly   281 --DTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANL 339
              |.|:|.||.|...:.    .:..||.|:.|:|.. |...|..||||::.::..|||..:
Frog   612 VKDACSGDSGGPFAVLF----HDTWFLVGVVSWGDG-CAEKGKYGVYTRVANYMPWIKETI 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	5/30 (17%)
		Tryp_SPc	108..338	CDD:238113	73/263 (28%)
		Tryp_SPc	108..335	CDD:214473	70/260 (27%)
proc.2	NP_001120289.1	GLA	19..80	CDD:214503
		EGF_CA	81..117	CDD:238011
		FXa_inhibition	123..160	CDD:373209
		Tryp_SPc	436..666	CDD:238113	73/265 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920