DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and zgc:165423

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_005164170.1	Gene:	zgc:165423 / 100101646	ZFINID:	ZDB-GENE-070720-11	Length:	538	Species:	Danio rerio

Alignment Length:	276	Identity:	76/276 - (27%)
Similarity:	121/276 - (43%)	Gaps:	40/276 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 DVLPNKQ--TCGQTTPVFRDRGAENAELNEYPWMVLLLYENRL-----SLI--RYVLTAAHCVIG 144
            |..|.:.  .||:.....:..|..||....:||.. .|:|:..     |||  :::|:||||
Zfish    19 DCQPTQSPPACGKAPLNTKIVGGTNASAGSWPWQA-SLHESGSHFCGGSLISDQWILSAAHC--- 79

  Fly   145 GYLTQNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPV 209
             :.:..:....:|.||..:.|.....    .:...|.|..||..:  .|.|:.||:|||.|..||
Zfish    80 -FPSNPNPSDYTVYLGRQSQDLPNPN----EVSKSVSQVIVHPLY--QGSTHDNDMALLHLSSPV 137

  Fly   210 RYTKKIQPICLLDAEFPLQDLNLQISGWDPTKSSQTL--------ITSTVKERNPADCLNRYPSF 266
            .::..|||:||........:..:.|:||...:|..:|        :...:...|..:||....|.
Zfish   138 TFSNYIQPVCLAADGSTFYNDTMWITGWGTIESGVSLPSPQILQEVNVPIVGNNLCNCLYGGGSS 202

  Fly   267 RSASQVCAGGQRKG-DTCAGISGSP-VMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIG 329
            .:.:.:|||..:.| |:|.|.||.| |:....:.|.     ||:.|:|:. |.....||||.::.
Zfish   203 ITNNMMCAGLMQGGKDSCQGDSGGPMVIKSFNTWVQ-----AGVVSFGKG-CADPNYPGVYARVS 261

  Fly   330 HFSEWI----KANLAP 341
            .:..||    :|:..|
Zfish   262 QYQNWISQYVRASFIP 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	70/250 (28%)
		Tryp_SPc	108..335	CDD:214473	68/243 (28%)
zgc:165423	XP_005164170.1	Tryp_SPc	37..267	CDD:214473	68/246 (28%)
		Tryp_SPc	38..269	CDD:238113	70/247 (28%)
		Tryp_SPc	299..473	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910