Protein Alignment CG18748 and Arrdc4

DIOPT Version :9

• Sequence 1: NP_001097703.1
• Gene: CG18748 / 59144
• FlyBaseID: FBgn0042105
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001036057.1
• Gene: Arrdc4 / 66412
• MGIID: 1913662
• Length: 415
• Species: Mus musculus
• Alignment Length: 419
• Identity: 108/419 - (25%)
• Similarity: 181/419 - (43%)
• Gaps: 77/419 - (18%)

  Fly     7 ILFHNNTQGVFYAGQMVAGQVTLSTDKAIQIKAIRLKLKGYAETHWTESK------TDSNNKSTS 65
            ::|.:.::|.:.:|:.|||.|.|...:.:.::.:||:.:|.|.:.|..|.      ...:..::|
Mouse    19 LVFEDESKGCYSSGETVAGHVLLEAAEPVALRGLRLEAQGRATSAWGPSAGARVCIGGGSPAASS 83

  Fly    66 ESYNGFEKYLSSKVYLLGSEISPEMA-LEPGTRSYNFACPIPIN-CPSSFEGTHGRIRYMVDVNI 128
            |     .:||:.::.||.:.....:. |:||...:.|...:|.. ..:||.|.:|.|:|.|...:
Mouse    84 E-----VEYLNLRLSLLEAPAGEGVTLLQPGKHEFPFRFQLPSEPLATSFTGKYGSIQYCVRAVL 143

  Fly   129 IQPWKYDSIFSRAFTVIQVMDINTYNSVSQVPVQAKTEKTFGVWPFRSDPLTLELNLPQTGFVPG 193
            .:|...|....|...|:..:|:||...::  |:....||..|.|.|.|.|::|.:.:.:.|:..|
Mouse   144 ERPQVPDQSVRRELQVVSHVDVNTPPLLT--PMLKTQEKMVGCWLFTSGPVSLSVKIERKGYCNG 206

  Fly   194 QTVPANVLIGNESKIRVHEVKVGLSMMITYYSDLSSG-SKCERKSVAKLKADGVLRNSRKMYDFQ 257
            :.:|....|.|.|. |:...|..:....||   |:|| :|..|..||.::.:.:...|...::.:
Mouse   207 EAIPIYAEIENCSS-RLVVPKAAIFQTQTY---LASGKTKTVRHMVANVRGNHIGSGSTDTWNGK 267

  Fly   258 LM-IPSTPPSCFHLCRIIKIGYQIEVVAKVKGMHINGT----LIMPVTICGVPI-------SPSA 310
            :: ||...||....| ||::.|.:.|.     :||.|.    |.:|:.|..:|.       |..|
Mouse   268 MLKIPPVTPSILDCC-IIRVDYSLAVY-----IHIPGAKRLMLELPLVIGTIPYSGFGRRNSSVA 326

  Fly   311 VQYT----------PQSSGPEAPEQRALTLIEGEGAFAPAAPPYPW----------------SEG 349
            .|::          |:.  ||||...|..:.|.|  |:...||||.                .|.
Mouse   327 SQFSMDMCWLALALPEQ--PEAPPNYADVVSEEE--FSRHVPPYPQPSDCDGEACYSMFACIQEF 387

  Fly   350 STLSPPNYAEAMHSHSDSEKQSESGNAQE 378
            ....||.|         ||.....|:|||
Mouse   388 RFQPPPLY---------SEVDPHPGDAQE 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18748	NP_001097703.1	Arrestin_N	5..151	CDD:278754	37/151 (25%)
		Arrestin_C	175..301	CDD:280848	35/131 (27%)
Arrdc4	NP_001036057.1	Arrestin_N	19..166	CDD:306778	37/151 (25%)
		Arrestin_C	188..315	CDD:214976	36/136 (26%)
		PPxY motif 1. /evidence=ECO:0000305	347..350		1/2 (50%)
		PPxY motif 2. /evidence=ECO:0000305	392..395		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I10262
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	145	1.000	Inparanoid score	I4409
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		otm42766
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.870