DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18748 and CG10086

DIOPT Version :9

Sequence 1:	NP_001097703.1	Gene:	CG18748 / 59144	FlyBaseID:	FBgn0042105	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_649736.3	Gene:	CG10086 / 40920	FlyBaseID:	FBgn0037517	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	437	Identity:	123/437 - (28%)
Similarity:	211/437 - (48%)	Gaps:	62/437 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CQILFHNNTQGVFYAGQMVAGQVTLSTDKAIQIKAIRLKLKGYAETHWTESK------TDSNNKS 63
            |.|.|..|..|.::.||::.|:|.::.:|..:::.|:|::.|||:..|...:      ..:..|.
  Fly     5 CMITFDQNEHGTYFTGQVITGKVIVNLNKTKKLRGIKLQISGYAQAQWRIRRHGKAVAIQNPKKR 69

  Fly    64 TSESYNGFEKYLSSKVYLLGSEISPEMALEPGTRSYNFACPIPINCPSSFEGTHGRIRYMVDVNI 128
            :...|:|.|.|::|..||:|||......::.||.:|.||||||.:|||||||.:|.|||:..|..
  Fly    70 SKHQYSGREDYIASTTYLMGSEQGSNFNMDAGTYTYTFACPIPSHCPSSFEGAYGHIRYLAKVTF 134

  Fly   129 IQPWKYDSIFSRAFTVIQVMDINTYNSVSQVPVQAKTEKTFGVWPFRSDPLTLELNLPQTGFVPG 193
            ::|...:...:..|||::::|:|....:.:.|...:..:.|.:  ..:.|:.|::.|.|.|:|||
  Fly   135 LKPGASNRTHNVGFTVLKLLDLNQETKMLREPASNEAVEHFCL--MHTKPVQLKVTLQQQGYVPG 197

  Fly   194 QTVPANVLIGNESKIRVHEVKVGLSMMITYYSDLSS-GSKCERKSVAKLKADGVLRNSRKMYDFQ 257
            |.:..:..:.|:|.....::.:.|.:..||.:|..| .:..|:..:.|.:...|..|:::.|...
  Fly   198 QFMLIHAHVRNDSSSDCRKLLIMLHLRATYTADTPSLRTTSEKIMLVKRECGPVAHNAQRTYTET 262

  Fly   258 LMIPSTPPSCFHLCRIIKIGYQIEVVAKVKGMHINGTLIMPVTICGVPISP--SAVQYTPQS--- 317
            |.||:|.|:|.||.:::::.|::.|||.:..:..|..||:||||..||::.  |...:.|.:
  Fly   263 LRIPATAPTCEHLSKVVRVSYEVRVVAVMNWLMANPRLIIPVTIGNVPLATAVSGPDFLPTNAFP 327

  Fly   318 SGPEAP------EQRALTL-------------------------------IEGEGAFAPAAPPYP 345
            ||...|      ..||:.|                               :|....|.|..|
  Fly   328 SGSSLPADLPCTSTRAMELAQMAASGVSNSGYEMAEDLEDFELPEDGDDELEAADDFVPDLP--- 389

  Fly   346 WSEGSTLSPPNYAEAMHSHSDSEKQSESGNAQEKSYKPLYPVFDLST 392
                    ||.|.:||...:|......:..::...:.|.|||||:.|
  Fly   390 --------PPTYEQAMFMTTDIADTDANTVSEASRFTPRYPVFDVDT 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18748	NP_001097703.1	Arrestin_N	5..151	CDD:278754	53/151 (35%)
CG18748	NP_001097703.1	Arrestin_C	175..301	CDD:280848	38/126 (30%)
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:278754	53/151 (35%)
CG10086	NP_649736.3	Arrestin_C	179..308	CDD:280848	40/128 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464041
Domainoid	1	1.000	139	1.000	Domainoid score	I9790
eggNOG	1	0.900	-	-		E1_KOG3780
Homologene	1	1.000	-	-		H119234
Inparanoid	1	1.050	43	1.000	Inparanoid score	I2088
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110793at6960
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		otm24709
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
	11	10.900