DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18748 and Arrdc2

DIOPT Version :9

Sequence 1:	NP_001097703.1	Gene:	CG18748 / 59144	FlyBaseID:	FBgn0042105	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_001100773.2	Gene:	Arrdc2 / 306344	RGDID:	1309659	Length:	407	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	104/394 - (26%)
Similarity:	177/394 - (44%)	Gaps:	47/394 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 TQGVFYAGQMVAGQVTLSTDKAIQIKAIRLKLKGYAETHWTESKTDSNNKSTSESYNGFEKYLSS 77
            |:.||:.||.|||:|.|....|.::.|:||:.:|.|..|||||::..::.:.::||:...:.::.
  Rat    20 TEPVFHGGQAVAGRVLLELAGAARVGALRLRARGRARAHWTESRSAGSSTAYTQSYSERVEVVNH 84

  Fly    78 KVYLLGSEISPEMALEPGTRSYNFACPIPINCPSSFEGTHGRIRYMVDVNIIQPWKYDSIFSRAF 142
            :..||..:....:.|..|...:.|:..:||:..:||||.||.:||.:...:.:||.......:.|
  Rat    85 RATLLAPDSGDIVMLPAGRHEFPFSFQLPISLVTSFEGKHGSVRYSIKATLHRPWVPARRARKVF 149

  Fly   143 TVIQVMDINTYNSVSQVPVQAKTEKTFGVWPFRSDPLTLELNLPQTGFVPGQTVPANVLIGNESK 207
            |||:.:||||...:.  |.....||....|......::|...:.:.|:.||:.:|....|.|.|
  Rat   150 TVIEPVDINTPALLE--PQAGAREKVARSWYCTRGLVSLSAKIDRKGYTPGEVIPIFAEIDNGS- 211

  Fly   208 IRVHEVKVGLSMMITYYSDLSSGSKCERKSVAKLKADGVLRNSRKMYDFQ-LMIPSTPPSCFHLC 271
            .|..:.:..|....|:.:..:...||  ..||.:..:.|....|.::..: |.||...||..| |
  Rat   212 TRAVQPRAALVQTQTFMARGARKQKC--AVVASVDGEPVGPGRRALWPGRALRIPPVGPSILH-C 273

  Fly   272 RIIKIGYQIEVVAKVKGMHINGTLI--MPVTICGVPISPSAVQYTPQSS---------------G 319
            |::.:.|.::|...:.|   :..|:  :|:.|..||:.|...:.....|               .
  Rat   274 RVLSVDYSLKVCVDIPG---SSKLLLELPLVIGTVPLHPLGSRSASVGSRASFLQDWGLCALMER 335

  Fly   320 PEAPEQRALTLIE------GEGAFAPAAPPYPWSEGSTLS---------PPNYAEAMHSHSDSEK 369
            ||||.:.:..:.|      .:|.|:....|...:||...:         ||.|:|     .|...
  Rat   336 PEAPPEYSEVVRESPQVAASQGLFSFLHDPDVTTEGPYFACLQEFRYRPPPLYSE-----EDPNP 395

  Fly   370 QSES 373
            .||:
  Rat   396 PSEA 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18748	NP_001097703.1	Arrestin_N	5..151	CDD:278754	45/137 (33%)
CG18748	NP_001097703.1	Arrestin_C	175..301	CDD:280848	30/128 (23%)
Arrdc2	NP_001100773.2	Arrestin_C	180..307	CDD:214976	32/133 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	96	1.000	Domainoid score	I7129
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		mtm8998
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.820