DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18748 and SPBC2D10.04

DIOPT Version :9

Sequence 1:	NP_001097703.1	Gene:	CG18748 / 59144	FlyBaseID:	FBgn0042105	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_596223.1	Gene:	SPBC2D10.04 / 2540410	PomBaseID:	SPBC2D10.04	Length:	658	Species:	Schizosaccharomyces pombe

Alignment Length:	475	Identity:	87/475 - (18%)
Similarity:	154/475 - (32%)	Gaps:	148/475 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 MVAGQVTLSTDKAIQIKAIRLKLKGYAETHWTES------KTDSNNKSTSESYNGFE-------- 72
            ::.|.:.|...|...|:.|.|...|.:.|.|.|.      .|..:....|.::..:|
pombe   175 LLRGALVLRVAKPANIRGISLSFTGRSRTEWPEGIPVKGHDTYEDKVIISHNWKFYEPTMKDADA 239

  Fly    73 -KYLSSKVYLLGSEIS-PEMA---------LEPGTRSYNFACPIPINC-PSSFEGTHGRIRYMVD 125
             ::.:....|:|.::. |..|         ..||..:|||...|| || |.|.|...|.:||.::
pombe   240 PQHGADVARLVGEQLPLPSSAAASLRGYSVFAPGEYTYNFDLAIP-NCFPESVEAKMGWVRYFLE 303

  Fly   126 VNIIQPWKYDSIFSRAFTVIQVMDINTYNSVSQV----PVQAKTEKTFGV---WPFRSDPLTLEL 183
            ..:.:...:.|            ::|....|..|    |....:.:...:   |..|   |..||
pombe   304 ATVERFGTFKS------------NLNGRTPVQLVRTPSPASLSSSELINISRDWDER---LHYEL 353

  Fly   184 NLPQTGFVPGQTVPANVLIGNESKIRVHEVKVGLSMMITYYSDLSSGSKCERKSVAKL------- 241
            .:....|..|:.||.........|:|::::.:.:.....|:.......:.:.|....|
pombe   354 QVSGKSFRLGEVVPITFRFLLLDKVRLYKLSISVVESSEYWCRSRKFHRVDPKRRVLLAERSAKH 418

  Fly   242 -----------KADGVLRNSRKMYDFQLMIPSTPPSCFHLC--------------RIIKIGYQIE 281
                       :.||:   |..:::|.:.:|:        |              :.||:.::::
pombe   419 QNTDNLFETPDEGDGL---SSAVFNFNVALPT--------CLVKERDRLTFDTTYKYIKVRHRLK 472

  Fly   282 VV-----------AKVKGMHIN---------------GTLI----------------MPVTICGV 304
            .:           .|.|...||               .||:                .|..:...
pombe   473 ALLVLSIENTENPEKRKYFEINIETPVRILSCRCVKDSTLLPPYESSSQGDNQVLLPCPCRLATT 537

  Fly   305 PISPSAV-QYTPQ----SSGPEAPEQRALTLIEGEGAF-APAAPPYPWS-----EGSTLSPPNYA 358
            .:.|:.| .:|.|    ||.|.|....|..:......| .|:..|.|:.     ......||||.
pombe   538 HVEPTEVTAFTTQSVLASSAPSAGRPAAAQISRPAQLFRIPSTNPPPFDGDVCPPACNTPPPNYD 602

  Fly   359 E---AMHSHSDSEKQSESGN 375
            |   .:.|.|..:.:::..|
pombe   603 ELFDVLSSISIQDCETDRAN 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18748	NP_001097703.1	Arrestin_N	5..151	CDD:278754	33/154 (21%)
CG18748	NP_001097703.1	Arrestin_C	175..301	CDD:280848	28/199 (14%)
SPBC2D10.04	NP_596223.1	Arrestin_N	178..308	CDD:304627	32/130 (25%)
SPBC2D10.04	NP_596223.1	Arrestin_C	345..506	CDD:214976	26/174 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	43	1.000	Inparanoid score	I2088
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050