DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18748 and arrd-15

DIOPT Version :9

Sequence 1:	NP_001097703.1	Gene:	CG18748 / 59144	FlyBaseID:	FBgn0042105	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_001254970.1	Gene:	arrd-15 / 191372	WormBaseID:	WBGene00014033	Length:	374	Species:	Caenorhabditis elegans

Alignment Length:	343	Identity:	85/343 - (24%)
Similarity:	146/343 - (42%)	Gaps:	52/343 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 AGQMVAGQVTL-STDKAIQIKAIRLKLKGYAETHWTESKTDSNNKSTSESYNGFEKYLSSKVYLL 82
            ||:....:|.| |:|....:.:...::||...|.|....||       :.:...:.|:.::|.|.
Worm    49 AGEFFNAKVLLDSSDPDTVVHSFCAEIKGIGRTGWVNIHTD-------KIFETEKTYIDTQVQLC 106

  Fly    83 GSEISPEMALEPGTRSYNFACPIPINCPSSFEGTHGRIRYMVDVNIIQPWKYDS--------IFS 139
            .|    ...|..|...:.....||:|||||:|...|.|||.:.|.:.......|        |.:
Worm   107 DS----GTCLPVGKHQFPVQIRIPLNCPSSYESQFGSIRYQMKVELRASTDQASCSEVFPLVILT 167

  Fly   140 RAFTVIQVMDINTYNSVSQVPVQAKTEKTFGVWPFRSDPLTLELNLPQTGFVPGQTVPANVLIGN 204
            |:|     .|....|::|.:..:.:.:.|....||..  ::|.::|.:|.|..|:::.|.|.|.|
Worm   168 RSF-----FDDVPLNAMSPIDFKDEVDFTCCTLPFGC--VSLNMSLTRTAFRIGESIEAVVTINN 225

  Fly   205 ESKIRVHEVKVGLSMMITYYSDLSSGSKCERKSVAKLKAD----GVLRNSRKMYDFQ---LMIPS 262
            .::..:.||.:.| :|.|.:...|.......|.:|:...:    |.:: ||...:|:   |.||.
Worm   226 RTRKGLKEVALQL-IMKTQFEARSRYEHVNEKKLAEQLIEMVPLGAVK-SRCRMEFEKCLLRIPD 288

  Fly   263 TPPSCFHLCR------IIKIGYQIEVVAKVKGMHINGTLIMPVTICGV--PISPSAVQY-----T 314
            ..|...:..|      ||.|.|.:::.| :.|:.....||  ||.||.  |...:|.|:     .
Worm   289 AAPPTQNYNRGAGESSIIAIHYVLKLTA-LPGIECEIPLI--VTSCGYMDPHKQAAFQHHLNRSK 350

  Fly   315 PQSSGPEAPEQRALTLIE 332
            .:.|..|..:::...::|
Worm   351 AKVSKTEQQQRKTRNIVE 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18748	NP_001097703.1	Arrestin_N	5..151	CDD:278754	36/140 (26%)
CG18748	NP_001097703.1	Arrestin_C	175..301	CDD:280848	35/138 (25%)
arrd-15	NP_001254970.1	Arrestin_N	49..148	CDD:304627	31/109 (28%)
arrd-15	NP_001254970.1	Arrestin_C	198..330	CDD:280848	35/138 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.020