DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18748 and arrd-28

DIOPT Version :9

Sequence 1:	NP_001097703.1	Gene:	CG18748 / 59144	FlyBaseID:	FBgn0042105	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_509710.2	Gene:	arrd-28 / 184759	WormBaseID:	WBGene00009000	Length:	650	Species:	Caenorhabditis elegans

Alignment Length:	287	Identity:	57/287 - (19%)
Similarity:	107/287 - (37%)	Gaps:	79/287 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 QIKAIRLKLKGYAETH--WTESKTDSNNKSTSESYNGFEKYLSSKVYLLGSEISPEMALEPGTRS 98
            :::::||.|.|.....  |.|                   :|..|..   :.:|.|..|.||..:
Worm   362 ELRSLRLILTGEVRVGGLWYE-------------------FLRFKAI---ANLSHETLLSPGEHN 404

  Fly    99 YNFACPIPINCPSSFE-----GTHG-RIRYMVDVNIIQPWKYDSIFSRAFTVIQVMDINTYNSVS 157
            :.|..|.   ..|.::     .|.| .|:||:..:.:...|  :.|.:...::....|:|:...:
Worm   405 FRFQLPF---ADSQYDTSILPPTLGDEIKYMIHASTVSLPK--NFFQQQCELLVDRFIDTWAKEA 464

  Fly   158 QVPVQAKTEKTFGVWPFRSDPLTLELNLPQTGFVPGQTVPANVLIGNE-----------SKIRVH 211
            ..|            |:..:....:::|.|..|..|:.|.. .|.|:|           .::||.
Worm   465 YKP------------PYTEEYGATKIHLSQRCFKRGKHVIV-ALQGSEPRYVKGTLVQKKRLRVP 516

  Fly   212 EVKVGLSMMITYYSDLSSGSKCERKSVAKLKADGVLRNSRKMYDFQLMIPSTPPSCFHLC--RII 274
            .||:             ..|.|.:::| ::..:.:   .||.:...:.||...|....:|  .::
Worm   517 NVKL-------------DESYCSQRNV-RIFEENI---HRKDHIHVMHIPFNIPPSIEICYWNVL 564

  Fly   275 KIGYQIEVVAKVKGMHINGTLIMPVTI 301
            :|.|..||...::|.|.:...| |:.|
Worm   565 QIEYHYEVEITLEGGHTHNHSI-PIWI 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18748	NP_001097703.1	Arrestin_N	5..151	CDD:278754	23/122 (19%)
CG18748	NP_001097703.1	Arrestin_C	175..301	CDD:280848	29/138 (21%)
arrd-28	NP_509710.2	Arrestin_C	153..278	CDD:214976
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100