Protein Alignment CG18748 and TXNIP

DIOPT Version :9

• Sequence 1: NP_001097703.1
• Gene: CG18748 / 59144
• FlyBaseID: FBgn0042105
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: XP_016855574.1
• Gene: TXNIP / 10628
• HGNCID: 16952
• Length: 395
• Species: Homo sapiens
• Alignment Length: 396
• Identity: 83/396 - (20%)
• Similarity: 165/396 - (41%)
• Gaps: 68/396 - (17%)

  Fly     6 QILFHNNTQGVFYAGQMVAGQVTLSTDKAIQIKAIRLKLKGYAETHWTESKTDSNNKSTSESYNG 70
            :::| |:.:.|:.:|:.|||:|.:...:..::||:|:...|.|:..|.:.....  |.||| |..
Human    11 EVVF-NDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGSQQC--KQTSE-YLR 71

  Fly    71 FEKYLSSKVYLLGSEISPE---MALEPGTR-SYNFACPIPIN-CPSSFEGTHGRIRYMVDVNIIQ 130
            :|..|     ||..:.:.|   :.:.||.: .|.|...:|.. ..:||:|.:|.:.|.|...:.:
Human    72 YEDTL-----LLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDR 131

  Fly   131 PWKYDSIFSRAFTVIQVMDINTYNSVSQVPVQAKTEKTFGVWPFRSDPLTLELNLPQTGFVPGQT 195
            |.:......:.|.|:.::|:||.:.::  ||.||.||...........:::...:.:.||..|..
Human   132 PSQPTQETKKNFEVVDLVDVNTPDLMA--PVSAKKEKKVSCMFIPDGRVSVSARIDRKGFCEGDE 194

  Fly   196 VPANVLIGNE-SKIRVHEVKVGLSMMITYYSDLSSG-SKCERKSVAKLKADGVLRNSRKMY-DFQ 257
            :..:....|. |:|.|.:..:     :..::.|::| :|...:.::.::.:.::..:...: ...
Human   195 ISIHADFENTCSRIVVPKAAI-----VARHTYLANGQTKVLTQKLSSVRGNHIISGTCASWRGKS 254

  Fly   258 LMIPSTPPSCFHLCRIIKIGYQIEVVAKVKGMHINGTLIMPVTI--------------------- 301
            |.:....||... |.|:::.|.:.:...|.|.. ...|.:|:.|
Human   255 LRVQKIRPSILG-CNILRVEYSLLIYVSVPGSK-KVILDLPLVIGSRSGLSSRTSSMASRTSSEM 317

  Fly   302 ----CGVPISPSA----VQYTPQSSGPEAPEQRALTLIEGEG-----AFAPAAPPYPWSEGSTLS 353
                ..:|.:|.|    :...|:....|:|....|..::|..     .:||        |...:.
Human   318 SWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQDSPIFMYAP--------EFKFMP 374

  Fly   354 PPNYAE 359
            ||.|.|
Human   375 PPTYTE 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18748	NP_001097703.1	Arrestin_N	5..151	CDD:278754	39/149 (26%)
		Arrestin_C	175..301	CDD:280848	20/128 (16%)
TXNIP	XP_016855574.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	146	1.000	Inparanoid score	I4428
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		mtm8525
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.870