Protein Alignment CG18747 and ALY1

DIOPT Version :10

• Sequence 1: NP_652650.2
• Gene: CG18747 / 59143
• FlyBaseID: FBgn0042104
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_012946.3
• Gene: ALY1 / 853891
• SGDID: S000001729
• Length: 915
• Species: Saccharomyces cerevisiae
• Alignment Length: 572
• Identity: 96/572 - (16%)
• Similarity: 179/572 - (31%)
• Gaps: 218/572 - (38%)

  Fly    19 AGQLVKGCATLKCDRSKEVQAVLLKVVGYSITKWSE----------------------------- 54
            |..:::|...::..:..:::::.:...|.|.|:|.|
Yeast    61 APSILRGSLIVRVLKPNKLKSISITFKGISRTEWPEGIPPKREEFSDVETVVNHTWPFYQADDGM 125

  Fly    55 ---------KSLGSTKLYVGREDYL-------------------SSNTYLVGSEQNN-------- 83
                     .:..|.:..:..||||                   :||..|...|:|:
Yeast   126 NSFTLEHHSSNNSSNRPSMSDEDYLLEKSGASVYIPPTAEPPKDNSNLSLDAYERNSLSSDNLSN 190

  Fly    84 -------THNNTHRLTIEAGVHSYNFTCQLPY-----QCPSSFEGR----HGCI----------- 121
                   :|:::..|.|:        ...||.     ..|::|.|.    |..|
Yeast   191 KPVSSDVSHDDSKLLAIQ--------KTPLPSSSRRGSVPANFHGNSLSPHTFISDLFTKTFSNS 247

  Fly   122 ----------RYIV------KVLLIRP----WKFDQAYTKGFTVLKMLDLNFDTPQLKSAAHSEG 166
                      .|:.      :|.:.||    :.|:|..::.:.  :.:..||.:.:.|.:...|.
Yeast   248 GATPSPEQEDNYLTPSKDSKEVFIFRPGDYIYTFEQPISQSYP--ESIKANFGSVEYKLSIDIER 310

  Fly   167 YRTFCCGPCKTDPLKLELHLPQAGYVPGQK----------------------------IPVTIVV 203
            :..|........|:|: :.||..|.|...:                            :|:....
Yeast   311 FGAFKSTIHTQLPIKV-VRLPSDGSVEETEAIAISKDWKDLLHYDVVIFSKEIVLNAFLPIDFHF 374

  Fly   204 VNNTAVAVSEIRLSLVMLVRY-YSVSPEHSRVERLIISRAKGESVLKQCTRSQTIDLPVPSTPPT 267
            .....|.:..||:.|...:.| .:.:..|.:..||..::   :.:|.:....:...:|..|.|..
Yeast   375 APLDKVTLHRIRIYLTESMEYTCNSNGNHEKARRLEPTK---KFLLAEHNGPKLPHIPAGSNPLK 436

  Fly   268 CVELSN---------LIQIAYQLEVEALVKSLREQQLMVMPVTVGTIPLAVSGIVVQQPPRRSAH 323
            .....|         |:...:|.||  .|.|.....:.:.|.|              ...:..||
Yeast   437 AKNRGNILLDEKSGDLVNKDFQFEV--FVPSKFTNSIRLHPDT--------------NYDKIKAH 485

  Fly   324 Y----------EGPDSRRNPPDELPMVTALESLPSDLASSAADSALPNYEESRHTQ----RGNI- 373
            :          :..|:|::  .|:.:.:.:..|  :...|.|::.||:||.  |.|    .||.
Yeast   486 HWIKICLRLSKKYGDNRKH--FEISIDSPIHIL--NQLCSHANTLLPSYES--HFQYCDEDGNFA 544

  Fly   374 --NEEELHA--FGSNEFAP----LYPVYS---------IPSPTPVLTANARN 408
              .:::.:|  ..||.|.|    ..||.|         |||..||:...|.:
Yeast   545 PAADQQNYASHHDSNIFFPKEVLSSPVLSPNVQKMNIRIPSDLPVVRNRAES 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18747	NP_652650.2	Arrestin_N	5..152	CDD:425619	33/244 (14%)
		Arrestin_C	176..307	CDD:214976	28/168 (17%)
ALY1	NP_012946.3	Arrestin_C	347..517	CDD:214976	28/192 (15%)