DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18747 and arrd-5

DIOPT Version :10

Sequence 1:NP_652650.2 Gene:CG18747 / 59143 FlyBaseID:FBgn0042104 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_496119.1 Gene:arrd-5 / 191469 WormBaseID:WBGene00014161 Length:378 Species:Caenorhabditis elegans


Alignment Length:440 Identity:109/440 - (24%)
Similarity:172/440 - (39%) Gaps:114/440 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 VVTCEISFDNNKHGTFYAGQLVKGCA--TLKCDRSKEVQAVLLKVVGYSITKWSEKSLGS-TKL- 62
            :.||.:.|..:. ..|..|:.|.|..  |:..|..| .:.|.::::|.:.|.|......: ||: 
 Worm     1 MATCLVEFAKSP-PVFSPGEKVTGNVKMTIPDDEFK-ARKVRMEMIGKAYTYWEGNVRNNHTKIK 63

  Fly    63 -------------YVGREDYLSSNTYLVGSEQNNTHNNTHRLTIEAGVHSYNFTCQLPYQCPSSF 114
                         :.|:..|....|.:..|:  ...|:     :.:|.|.:.|:.|||:..|.||
 Worm    64 NGDIARVRHNCADHKGKIVYCRFETIVWKSD--GAKND-----MPSGPHIFPFSFQLPHWAPPSF 121

  Fly   115 EGRHGCIRYIVKVLLIRPWKFDQAYTKGFTVLKMLDL----NFDTPQLKSAAHSEGYRTFCCGPC 175
            ||..|.|||.:||.:.||||||..:....|||..:||    |...|..|......|...:     
 Worm   122 EGDLGFIRYFIKVEIDRPWKFDDKFITCLTVLPNIDLRLIPNSQVPSKKHVCEEFGAVLW----- 181

  Fly   176 KTDPLKLELHLPQAGYVPGQKIPVTIVVVNNTAVAVSEIRLSLVMLVRYYSVSP----EHS---- 232
            |...:::||.||:.|:|.|:.||||::|.|.|:.:..:|.|.||..|.|.....    .||    
 Worm   182 KNGLVRMELRLPKQGFVCGENIPVTMIVDNKTSKSFKKISLRLVQRVTYTGFRDGFVNSHSQPCI 246

  Fly   233 -----------------RVERLIISRAKGESVLKQCTRSQTIDLPVPSTP-PTCVELSNLIQIAY 279
                             |||...||....:..:.: ...|.::.|:|..| |...:...:|.:.|
 Worm   247 GNEKEKITYATRLNAQTRVEERQISETNIDIKIDK-NEKQEVEKPIPLPPLPPSTKTCEIIDVEY 310

  Fly   280 QLEVEALVK-SLREQQLMVMPVTVGTIPLAVSGIVVQQPPRRSAHYEGPDSRRNPPDELPMVTAL 343
            .|:|:.... :|:....:.:...:||:|:         .|.|...|:                  
 Worm   311 FLKVKMSTSGALKSAVKLELAFIIGTMPI---------DPERKYEYK------------------ 348

  Fly   344 ESLPSDLASSAADSALPNYEESRHTQRGNINEEELHAFGSNEFAPLYPVY 393
                ..:...||.|.     ::|..|:               |||||||:
 Worm   349 ----KSVFGFAATSL-----KNRDVQK---------------FAPLYPVF 374

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18747NP_652650.2 Arrestin_N 5..152 CDD:425619 48/167 (29%)
Arrestin_C 176..307 CDD:214976 40/157 (25%)
arrd-5NP_496119.1 Arrestin_N 4..158 CDD:425619 46/162 (28%)
Arrestin_C 182..338 CDD:214976 40/156 (26%)

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