Protein Alignment CG18747 and arrd-22

DIOPT Version :10

• Sequence 1: NP_652650.2
• Gene: CG18747 / 59143
• FlyBaseID: FBgn0042104
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_503955.1
• Gene: arrd-22 / 188642
• WormBaseID: WBGene00020612
• Length: 456
• Species: Caenorhabditis elegans
• Alignment Length: 483
• Identity: 119/483 - (24%)
• Similarity: 203/483 - (42%)
• Gaps: 128/483 - (26%)

  Fly     6 EISFDNNKHGTFYAGQLVKGCATLKCDRSKEVQAVLLKVVGYSITKWSEKSLGSTKL-------Y 63
            ::.||.... .|..||.:.|...|...:....:||.:|:||.:.|.|.... .|.||       |
 Worm     8 QVIFDQPDE-VFLPGQPISGRVVLTTKKKLSARAVNIKIVGLAHTSWKNYE-NSCKLSFHRIVSY 70

  Fly    64 VGREDYLSSNT-YLVGSEQNNTHNNTHRL--------TIEAGVHSYNFTCQLPYQCPSSFEGRHG 119
            .....|.|:|. ||         :.|..|        .:.||.:::.|:..||...|.||||::|
 Worm    71 RPHGVYYSANVKYL---------DYTQLLWTCGEGPKELNAGEYAWPFSYTLPLNIPPSFEGKYG 126

  Fly   120 CIRYIVKVLLIRPWKFDQAYTKGFTVLKMLDLNFD----TPQLKSAAHSEGYRTFCCGPC-KTDP 179
            .:||.|||.:.|||:.|:|.....||..:||||..    ||....|:.:.|    ||  | |...
 Worm   127 YLRYTVKVEVDRPWRVDKAKKMCITVSPLLDLNVIPHSLTPINTQASENLG----CC--CFKNGF 185

  Fly   180 LKLELHLPQAGYVPGQKIPVTIVVVNNTAVAVSEIRLSLVMLVRY--------------YSVSPE 230
            |::.:::|:.|:|||:.:|:.|.::|:::....:|...::...::              .::|.:
 Worm   186 LEMNVNIPKTGFVPGETVPLNIHLINHSSSTAKKIEAKILQQCKFTGYKDGATYNYGGDENMSEK 250

  Fly   231 HSRV-----------ERLIISRAKGESVLKQCTRSQTIDLPVPSTPPTCVELSNLIQIAY--QLE 282
            ..|:           ::|::: ||.|       ....::|.:||..||..:.|.::.:.|  ||:
 Worm   251 AQRIMFDTKTVVRESQKLVVA-AKNE-------HKFVLELRIPSVTPTINQFSPVVTVEYLIQLK 307

  Fly   283 VEALVKSLREQQLMVMPVTVGTIPLAVSGIVVQQ--PPRRSAHYEGPD---SRRNPPDE------ 336
            |:....|..|.:... .:.:|::|       ::|  ||  |.:.:.|.   |:..|..|
 Worm   308 VDTSAMSHSEVRCET-SILLGSVP-------IRQCLPP--SYYQQDPSVLPSKPTPIGEGVAPPP 362

  Fly   337 ----LPMVTALES-----LPSDLASSAADSAL------------------PNYEESRHTQRGNIN 374
                |||....|.     .|..|..:..|..|                  |:|:||.:.:.|.:
 Worm   363 GYGSLPMTDDSEKGTDAPYPLGLYPNVNDVNLPYPSVVQDGNAVIPSAPPPSYQESMYGKGGTV- 426

  Fly   375 EEELHAFGSNEFAPLYPVYS---IPSPT 399
               |.|..:..:.|.|||::   :.:||
 Worm   427 ---LDAKENEPYVPKYPVFNNLPVYNPT 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18747	NP_652650.2	Arrestin_N	5..152	CDD:425619	50/161 (31%)
		Arrestin_C	176..307	CDD:214976	30/157 (19%)
arrd-22	NP_503955.1	Arrestin_N	7..159	CDD:425619	50/161 (31%)
		Arrestin_C	182..330	CDD:214976	30/156 (19%)